FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.955515 View
ENSG00000075340 ADD2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.954861 View
ENSG00000077782 FGFR1 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.954331 View
ENSG00000077782 FGFR1 ENSG00000103496 STX4 H. sapiens SDL Slorth 0.953649 View
ENSG00000077782 FGFR1 ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.953577 View
ENSG00000077782 FGFR1 ENSG00000174775 HRAS H. sapiens SDL Slorth 0.953293 View
ENSG00000077782 FGFR1 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.953239 View
ENSG00000077782 FGFR1 ENSG00000179218 CALR H. sapiens SDL Slorth 0.952584 View
ENSG00000070010 UFD1L ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.952204 View
ENSG00000004700 RECQL ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.95212 View
ENSG00000077782 FGFR1 ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.952093 View
ENSG00000077782 FGFR1 ENSG00000102755 FLT1 H. sapiens SDL Slorth 0.952035 View
ENSG00000077782 FGFR1 ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.951765 View
ENSG00000007908 SELE ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.950971 View
ENSG00000077782 FGFR1 ENSG00000165731 RET H. sapiens SDL Slorth 0.950483 View
ENSG00000077782 FGFR1 ENSG00000118515 SGK1 H. sapiens SDL Slorth 0.949765 View
ENSG00000077782 FGFR1 ENSG00000113578 FGF1 H. sapiens SDL Slorth 0.949386 View
ENSG00000077380 DYNC1I2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.94923 View
ENSG00000077782 FGFR1 ENSG00000204103 MAFB H. sapiens SDL Slorth 0.949091 View
ENSG00000077782 FGFR1 ENSG00000178997 EXD1 H. sapiens SDL Slorth 0.948587 View
ENSG00000077782 FGFR1 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.948551 View
ENSG00000077092 RARB ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.947851 View
ENSG00000077782 FGFR1 ENSG00000148200 NR6A1 H. sapiens SDL Slorth 0.947768 View
ENSG00000010810 FYN ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.947587 View
ENSG00000077279 DCX ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.947108 View
ENSG00000077782 FGFR1 ENSG00000101096 NFATC2 H. sapiens SDL Slorth 0.946748 View
ENSG00000067141 NEO1 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.946681 View
ENSG00000063660 GPC1 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.946681 View
ENSG00000077782 FGFR1 ENSG00000176749 CDK5R1 H. sapiens SDL Slorth 0.945986 View
ENSG00000077782 FGFR1 ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.945232 View
ENSG00000077782 FGFR1 ENSG00000147162 OGT H. sapiens SDL Slorth 0.945179 View
ENSG00000077782 FGFR1 ENSG00000085449 WDFY1 H. sapiens SDL Slorth 0.945029 View
ENSG00000077782 FGFR1 ENSG00000110031 LPXN H. sapiens SDL Slorth 0.944001 View
ENSG00000066455 GOLGA5 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.943844 View
ENSG00000077782 FGFR1 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.94351 View
ENSG00000012048 BRCA1 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.943501 View
ENSG00000077782 FGFR1 ENSG00000141380 SS18 H. sapiens SDL Slorth 0.942946 View
ENSG00000061918 GUCY1B3 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.942754 View
ENSG00000004897 CDC27 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.942608 View
ENSG00000077782 FGFR1 ENSG00000140575 IQGAP1 H. sapiens SDL Slorth 0.942455 View