FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000100311 PDGFB H. sapiens SDL Slorth 0.942373 View
ENSG00000072736 NFATC3 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.942346 View
ENSG00000077782 FGFR1 ENSG00000120149 MSX2 H. sapiens SDL Slorth 0.942295 View
ENSG00000077782 FGFR1 ENSG00000177606 JUN H. sapiens SDL Slorth 0.941999 View
ENSG00000077782 FGFR1 ENSG00000100644 HIF1A H. sapiens SDL Slorth 0.94164 View
ENSG00000077782 FGFR1 ENSG00000185022 MAFF H. sapiens SDL Slorth 0.941183 View
ENSG00000067829 IDH3G ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.941056 View
ENSG00000041353 RAB27B ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.940495 View
ENSG00000077782 FGFR1 ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.94029 View
ENSG00000077782 FGFR1 ENSG00000135604 STX11 H. sapiens SDL Slorth 0.940234 View
ENSG00000077782 FGFR1 ENSG00000160867 FGFR4 H. sapiens SDL Slorth 0.940174 View
ENSG00000077782 FGFR1 ENSG00000104365 IKBKB H. sapiens SDL Slorth 0.940031 View
ENSG00000077782 FGFR1 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.939117 View
ENSG00000001626 CFTR ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.939052 View
ENSG00000077782 FGFR1 ENSG00000106571 GLI3 H. sapiens SDL Slorth 0.937723 View
ENSG00000077782 FGFR1 ENSG00000120500 ARR3 H. sapiens SDL Slorth 0.937233 View
ENSG00000077782 FGFR1 ENSG00000163485 ADORA1 H. sapiens SDL Slorth 0.936243 View
ENSG00000077097 TOP2B ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.936169 View
ENSG00000062822 POLD1 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.935915 View
ENSG00000048462 TNFRSF17 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.93583 View
ENSG00000077782 FGFR1 ENSG00000101665 SMAD7 H. sapiens SDL Slorth 0.935183 View
ENSG00000077782 FGFR1 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.934729 View
ENSG00000077782 FGFR1 ENSG00000176720 BOK H. sapiens SDL Slorth 0.934725 View
ENSG00000073111 MCM2 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.934711 View
ENSG00000077782 FGFR1 ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.934553 View
ENSG00000077782 FGFR1 ENSG00000080815 PSEN1 H. sapiens SDL Slorth 0.934352 View
ENSG00000077782 FGFR1 ENSG00000109519 GRPEL1 H. sapiens SDL Slorth 0.934347 View
ENSG00000075624 ACTB ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.933814 View
ENSG00000010671 BTK ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.933347 View
ENSG00000077782 FGFR1 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.933334 View
ENSG00000077782 FGFR1 ENSG00000166501 PRKCB H. sapiens SDL Slorth 0.933099 View
ENSG00000072422 RHOBTB1 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.933044 View
ENSG00000008853 RHOBTB2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.933044 View
ENSG00000077782 FGFR1 ENSG00000205726 ITSN1 H. sapiens SDL Slorth 0.93284 View
ENSG00000072315 TRPC5 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.932486 View
ENSG00000070718 AP3M2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.93223 View
ENSG00000077782 FGFR1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931693 View
ENSG00000077782 FGFR1 ENSG00000110092 CCND1 H. sapiens SDL Slorth 0.931645 View
ENSG00000077782 FGFR1 ENSG00000204435 CSNK2B H. sapiens SDL Slorth 0.931642 View
ENSG00000077782 FGFR1 ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.931062 View