FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000129559 NEDD8 H. sapiens SSL Slorth 0.923533 View
ENSG00000077782 FGFR1 ENSG00000136100 VPS36 H. sapiens SDL Slorth 0.922628 View
ENSG00000077782 FGFR1 ENSG00000132466 ANKRD17 H. sapiens SDL Slorth 0.922478 View
ENSG00000077782 FGFR1 ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.921903 View
ENSG00000077782 FGFR1 ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.921847 View
ENSG00000077782 FGFR1 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.921633 View
ENSG00000061273 HDAC7 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.921294 View
ENSG00000077782 FGFR1 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.921112 View
ENSG00000077782 FGFR1 ENSG00000115904 SOS1 H. sapiens SDL Slorth 0.921071 View
ENSG00000077782 FGFR1 ENSG00000082898 XPO1 H. sapiens SSL Slorth 0.920739 View
ENSG00000077782 FGFR1 ENSG00000110048 OSBP H. sapiens SDL Slorth 0.920683 View
ENSG00000077782 FGFR1 ENSG00000081913 PHLPP1 H. sapiens SDL Slorth 0.920549 View
ENSG00000077782 FGFR1 ENSG00000152822 GRM1 H. sapiens SDL Slorth 0.920479 View
ENSG00000077782 FGFR1 ENSG00000079335 CDC14A H. sapiens SDL Slorth 0.919876 View
ENSG00000077782 FGFR1 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.919472 View
ENSG00000072062 PRKACA ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.919364 View
ENSG00000077782 FGFR1 ENSG00000132437 DDC H. sapiens SDL Slorth 0.919276 View
ENSG00000077782 FGFR1 ENSG00000083168 KAT6A H. sapiens SDL Slorth 0.919269 View
ENSG00000077782 FGFR1 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.919131 View
ENSG00000077782 FGFR1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.919028 View
ENSG00000077782 FGFR1 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.919018 View
ENSG00000070404 FSTL3 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.91839 View
ENSG00000069869 NEDD4 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.91809 View
ENSG00000048540 LMO3 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.918061 View
ENSG00000077782 FGFR1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.917852 View
ENSG00000005882 PDK2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.91774 View
ENSG00000077782 FGFR1 ENSG00000147010 SH3KBP1 H. sapiens SDL Slorth 0.917331 View
ENSG00000077782 FGFR1 ENSG00000078747 ITCH H. sapiens SSL Slorth 0.917121 View
ENSG00000077782 FGFR1 ENSG00000128881 TTBK2 H. sapiens SDL Slorth 0.917079 View
ENSG00000077782 FGFR1 ENSG00000133703 KRAS H. sapiens SDL Slorth 0.91688 View
ENSG00000072518 MARK2 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.916638 View
ENSG00000005007 UPF1 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.916603 View
ENSG00000077782 FGFR1 ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.916589 View
ENSG00000077782 FGFR1 ENSG00000198876 DCAF12 H. sapiens SDL Slorth 0.916435 View
ENSG00000077782 FGFR1 ENSG00000102996 MMP15 H. sapiens SDL Slorth 0.916214 View
ENSG00000070476 ZXDC ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.916055 View
ENSG00000077782 FGFR1 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.915988 View
ENSG00000011454 RABGAP1 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.915754 View
ENSG00000077782 FGFR1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.915674 View
ENSG00000077782 FGFR1 ENSG00000167548 KMT2D H. sapiens SDL Slorth 0.915555 View