ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000158186 MRAS H. sapiens SDL Slorth 0.987417 View
ENSG00000091831 ESR1 ENSG00000114737 CISH H. sapiens SDL Slorth 0.987409 View
ENSG00000091831 ESR1 ENSG00000111859 NEDD9 H. sapiens SDL Slorth 0.987405 View
ENSG00000091831 ESR1 ENSG00000146872 TLK2 H. sapiens SDL Slorth 0.987385 View
ENSG00000091831 ESR1 ENSG00000145555 MYO10 H. sapiens SDL Slorth 0.98738 View
ENSG00000091831 ESR1 ENSG00000198901 PRC1 H. sapiens SDL Slorth 0.987271 View
ENSG00000091831 ESR1 ENSG00000139567 ACVRL1 H. sapiens SDL Slorth 0.987229 View
ENSG00000091831 ESR1 ENSG00000115290 GRB14 H. sapiens SDL Slorth 0.987203 View
ENSG00000091831 ESR1 ENSG00000112290 WASF1 H. sapiens SDL Slorth 0.987197 View
ENSG00000091831 ESR1 ENSG00000127955 GNAI1 H. sapiens SDL Slorth 0.987192 View
ENSG00000091831 ESR1 ENSG00000248333 CDK11B H. sapiens SDL Slorth 0.987154 View
ENSG00000091831 ESR1 ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.98714 View
ENSG00000091831 ESR1 ENSG00000175305 CCNE2 H. sapiens SDL Slorth 0.987088 View
ENSG00000091831 ESR1 ENSG00000142875 PRKACB H. sapiens SDL Slorth 0.987063 View
ENSG00000091831 ESR1 ENSG00000155974 GRIP1 H. sapiens SDL Slorth 0.987044 View
ENSG00000091831 ESR1 ENSG00000178188 SH2B1 H. sapiens SDL Slorth 0.987044 View
ENSG00000091831 ESR1 ENSG00000116473 RAP1A H. sapiens SDL Slorth 0.987028 View
ENSG00000091831 ESR1 ENSG00000185359 HGS H. sapiens SDL Slorth 0.986933 View
ENSG00000091831 ESR1 ENSG00000106144 CASP2 H. sapiens SDL Slorth 0.98693 View
ENSG00000091831 ESR1 ENSG00000111348 ARHGDIB H. sapiens SDL Slorth 0.986914 View
ENSG00000091831 ESR1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.986886 View
ENSG00000091831 ESR1 ENSG00000164985 PSIP1 H. sapiens SDL Slorth 0.986818 View
ENSG00000091831 ESR1 ENSG00000166483 WEE1 H. sapiens SDL Slorth 0.986797 View
ENSG00000091831 ESR1 ENSG00000106615 RHEB H. sapiens SDL Slorth 0.986794 View
ENSG00000091831 ESR1 ENSG00000140262 TCF12 H. sapiens SDL Slorth 0.986783 View
ENSG00000091831 ESR1 ENSG00000178562 CD28 H. sapiens SDL Slorth 0.98678 View
ENSG00000091831 ESR1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.986772 View
ENSG00000091831 ESR1 ENSG00000198286 CARD11 H. sapiens SDL Slorth 0.986752 View
ENSG00000091831 ESR1 ENSG00000180353 HCLS1 H. sapiens SDL Slorth 0.986731 View
ENSG00000091831 ESR1 ENSG00000113578 FGF1 H. sapiens SDL Slorth 0.986704 View
ENSG00000091831 ESR1 ENSG00000102882 MAPK3 H. sapiens SDL Slorth 0.986696 View
ENSG00000091831 ESR1 ENSG00000107263 RAPGEF1 H. sapiens SDL Slorth 0.98665 View
ENSG00000091831 ESR1 ENSG00000162924 REL H. sapiens SDL Slorth 0.986638 View
ENSG00000091831 ESR1 ENSG00000164056 SPRY1 H. sapiens SDL Slorth 0.986634 View
ENSG00000091831 ESR1 ENSG00000101558 VAPA H. sapiens SDL Slorth 0.98659 View
ENSG00000091831 ESR1 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.986589 View
ENSG00000091831 ESR1 ENSG00000114062 UBE3A H. sapiens SDL Slorth 0.986566 View
ENSG00000091831 ESR1 ENSG00000165731 RET H. sapiens SDL Slorth 0.986563 View
ENSG00000091831 ESR1 ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.98656 View
ENSG00000091831 ESR1 ENSG00000169564 PCBP1 H. sapiens SDL Slorth 0.986536 View