ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000133056 PIK3C2B H. sapiens SDL Slorth 0.983611 View
ENSG00000091831 ESR1 ENSG00000155849 ELMO1 H. sapiens SDL Slorth 0.983599 View
ENSG00000091831 ESR1 ENSG00000121067 SPOP H. sapiens SDL Slorth 0.98359 View
ENSG00000091831 ESR1 ENSG00000177105 RHOG H. sapiens SDL Slorth 0.983587 View
ENSG00000013441 CLK1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983583 View
ENSG00000091831 ESR1 ENSG00000139318 DUSP6 H. sapiens SDL Slorth 0.98354 View
ENSG00000091831 ESR1 ENSG00000143256 PFDN2 H. sapiens SDL Slorth 0.983526 View
ENSG00000091831 ESR1 ENSG00000168959 GRM5 H. sapiens SDL Slorth 0.983515 View
ENSG00000007264 MATK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983505 View
ENSG00000091831 ESR1 ENSG00000136352 NKX2-1 H. sapiens SDL Slorth 0.983494 View
ENSG00000091831 ESR1 ENSG00000138592 USP8 H. sapiens SDL Slorth 0.983483 View
ENSG00000082146 STRADB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983481 View
ENSG00000008256 CYTH3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983462 View
ENSG00000091831 ESR1 ENSG00000126351 THRA H. sapiens SDL Slorth 0.983416 View
ENSG00000091831 ESR1 ENSG00000213639 PPP1CB H. sapiens SDL Slorth 0.983394 View
ENSG00000091831 ESR1 ENSG00000150457 LATS2 H. sapiens SDL Slorth 0.983356 View
ENSG00000049323 LTBP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983348 View
ENSG00000091831 ESR1 ENSG00000125618 PAX8 H. sapiens SDL Slorth 0.983327 View
ENSG00000015285 WAS ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983324 View
ENSG00000090520 DNAJB11 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983321 View
ENSG00000060237 WNK1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983299 View
ENSG00000091831 ESR1 ENSG00000100591 AHSA1 H. sapiens SDL Slorth 0.983246 View
ENSG00000091831 ESR1 ENSG00000167548 KMT2D H. sapiens SDL Slorth 0.983232 View
ENSG00000091831 ESR1 ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.983227 View
ENSG00000091831 ESR1 ENSG00000165527 ARF6 H. sapiens SDL Slorth 0.983209 View
ENSG00000091831 ESR1 ENSG00000115085 ZAP70 H. sapiens SDL Slorth 0.983204 View
ENSG00000091831 ESR1 ENSG00000166592 RRAD H. sapiens SDL Slorth 0.98316 View
ENSG00000091831 ESR1 ENSG00000116128 BCL9 H. sapiens SDL Slorth 0.983157 View
ENSG00000091831 ESR1 ENSG00000136527 TRA2B H. sapiens SDL Slorth 0.983152 View
ENSG00000091831 ESR1 ENSG00000141582 CBX4 H. sapiens SDL Slorth 0.983143 View
ENSG00000091831 ESR1 ENSG00000119041 GTF3C3 H. sapiens SDL Slorth 0.983121 View
ENSG00000091831 ESR1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.983094 View
ENSG00000091831 ESR1 ENSG00000103510 KAT8 H. sapiens SDL Slorth 0.983075 View
ENSG00000066455 GOLGA5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.983053 View
ENSG00000091831 ESR1 ENSG00000136931 NR5A1 H. sapiens SDL Slorth 0.98305 View
ENSG00000091831 ESR1 ENSG00000157404 KIT H. sapiens SDL Slorth 0.983046 View
ENSG00000091831 ESR1 ENSG00000168439 STIP1 H. sapiens SDL Slorth 0.983041 View
ENSG00000091831 ESR1 ENSG00000124788 ATXN1 H. sapiens SDL Slorth 0.98303 View
ENSG00000091831 ESR1 ENSG00000129514 FOXA1 H. sapiens SDL Slorth 0.982997 View
ENSG00000091831 ESR1 ENSG00000147065 MSN H. sapiens SDL Slorth 0.982992 View