ERCC2

ENSG00000104884 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008094 DNA-dependent ATPase activity
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0004672 protein kinase activity
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity

Drugs

No drugs in record

Diseases

Disease Name
skin basal cell
skin squamous cell
melanoma

Orthologs

Gene Organism
RAD3 S. cerevisiae
Y50D7A.11 C. elegans
Xpd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000104884 ERCC2 ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.937908 View
ENSG00000004487 KDM1A ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.937791 View
ENSG00000104884 ERCC2 ENSG00000181788 SIAH2 H. sapiens SDL Slorth 0.937132 View
ENSG00000104884 ERCC2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.936705 View
ENSG00000096717 SIRT1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.93661 View
ENSG00000104884 ERCC2 ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.936221 View
ENSG00000104884 ERCC2 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.935582 View
ENSG00000102882 MAPK3 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.935468 View
ENSG00000100030 MAPK1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.935082 View
ENSG00000104884 ERCC2 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.93441 View
ENSG00000104884 ERCC2 ENSG00000131467 PSME3 H. sapiens SDL Slorth 0.933701 View
ENSG00000104884 ERCC2 ENSG00000110092 CCND1 H. sapiens SDL Slorth 0.933376 View
ENSG00000101665 SMAD7 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.933259 View
ENSG00000072401 UBE2D1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.933142 View
ENSG00000094804 CDC6 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.932064 View
ENSG00000104884 ERCC2 ENSG00000183207 RUVBL2 H. sapiens SDL Slorth 0.931502 View
ENSG00000104884 ERCC2 ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.93142 View
ENSG00000047410 TPR ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.931028 View
ENSG00000104884 ERCC2 ENSG00000131759 RARA H. sapiens SDL Slorth 0.93082 View
ENSG00000104884 ERCC2 ENSG00000150907 FOXO1 H. sapiens SDL Slorth 0.930625 View
ENSG00000100387 RBX1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.929522 View
ENSG00000075624 ACTB ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.929406 View
ENSG00000101412 E2F1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.929185 View
ENSG00000104884 ERCC2 ENSG00000187735 TCEA1 H. sapiens SDL Slorth 0.928618 View
ENSG00000104884 ERCC2 ENSG00000197299 BLM H. sapiens SDL Slorth 0.928098 View
ENSG00000004897 CDC27 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.927342 View
ENSG00000104884 ERCC2 ENSG00000185345 PARK2 H. sapiens SDL Slorth 0.927232 View
ENSG00000104884 ERCC2 ENSG00000141551 CSNK1D H. sapiens SDL Slorth 0.926912 View
ENSG00000104884 ERCC2 ENSG00000109320 NFKB1 H. sapiens SDL Slorth 0.926087 View
ENSG00000073111 MCM2 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.925803 View
ENSG00000062822 POLD1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.924807 View
ENSG00000104884 ERCC2 ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.924553 View
ENSG00000100138 SNU13 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.924215 View
ENSG00000101412 E2F1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.923989 View
ENSG00000104884 ERCC2 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.923454 View
ENSG00000068654 POLR1A ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.923449 View
ENSG00000104884 ERCC2 ENSG00000118515 SGK1 H. sapiens SDL Slorth 0.923002 View
ENSG00000092201 SUPT16H ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.922488 View
ENSG00000023445 BIRC3 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.92153 View
ENSG00000094804 CDC6 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.92153 View