BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000130939 UBE4B H. sapiens SDL Slorth 0.962864 View
ENSG00000010671 BTK ENSG00000133703 KRAS H. sapiens SSL Slorth 0.962823 View
ENSG00000010671 BTK ENSG00000141543 EIF4A3 H. sapiens SDL Slorth 0.962422 View
ENSG00000010671 BTK ENSG00000177606 JUN H. sapiens SDL Slorth 0.96219 View
ENSG00000010671 BTK ENSG00000186468 RPS23 H. sapiens SDL Slorth 0.962147 View
ENSG00000010671 BTK ENSG00000142534 RPS11 H. sapiens SDL Slorth 0.962139 View
ENSG00000010671 BTK ENSG00000105372 RPS19 H. sapiens SDL Slorth 0.962069 View
ENSG00000010671 BTK ENSG00000171105 INSR H. sapiens SDL Slorth 0.962012 View
ENSG00000010671 BTK ENSG00000137818 RPLP1 H. sapiens SDL Slorth 0.962012 View
ENSG00000010671 BTK ENSG00000078747 ITCH H. sapiens SDL Slorth 0.961929 View
ENSG00000010671 BTK ENSG00000187790 FANCM H. sapiens SDL Slorth 0.961914 View
ENSG00000010671 BTK ENSG00000185345 PARK2 H. sapiens SDL Slorth 0.961473 View
ENSG00000010671 BTK ENSG00000108298 RPL19 H. sapiens SDL Slorth 0.961329 View
ENSG00000010671 BTK ENSG00000197728 RPS26 H. sapiens SDL Slorth 0.961329 View
ENSG00000010671 BTK ENSG00000135341 MAP3K7 H. sapiens SDL Slorth 0.961323 View
ENSG00000010671 BTK ENSG00000124614 RPS10 H. sapiens SDL Slorth 0.961322 View
ENSG00000010671 BTK ENSG00000114423 CBLB H. sapiens SDL Slorth 0.961283 View
ENSG00000010671 BTK ENSG00000122026 RPL21 H. sapiens SDL Slorth 0.961266 View
ENSG00000010671 BTK ENSG00000188846 RPL14 H. sapiens SDL Slorth 0.961266 View
ENSG00000010671 BTK ENSG00000114391 RPL24 H. sapiens SDL Slorth 0.961266 View
ENSG00000010671 BTK ENSG00000149311 ATM H. sapiens SDL Slorth 0.960981 View
ENSG00000010671 BTK ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.960789 View
ENSG00000010671 BTK ENSG00000145592 RPL37 H. sapiens SDL Slorth 0.960786 View
ENSG00000010671 BTK ENSG00000148606 POLR3A H. sapiens SDL Slorth 0.960719 View
ENSG00000010671 BTK ENSG00000050820 BCAR1 H. sapiens SDL Slorth 0.960431 View
ENSG00000010671 BTK ENSG00000142541 RPL13A H. sapiens SDL Slorth 0.960335 View
ENSG00000010671 BTK ENSG00000134308 YWHAQ H. sapiens SDL Slorth 0.96032 View
ENSG00000010671 BTK ENSG00000172809 RPL38 H. sapiens SDL Slorth 0.959723 View
ENSG00000010671 BTK ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.958962 View
ENSG00000010671 BTK ENSG00000104365 IKBKB H. sapiens SDL Slorth 0.958949 View
ENSG00000010671 BTK ENSG00000196419 XRCC6 H. sapiens SDL Slorth 0.958562 View
ENSG00000010671 BTK ENSG00000177889 UBE2N H. sapiens SDL Slorth 0.958444 View
ENSG00000010671 BTK ENSG00000171858 RPS21 H. sapiens SDL Slorth 0.958257 View
ENSG00000010671 BTK ENSG00000161016 RPL8 H. sapiens SDL Slorth 0.957524 View
ENSG00000010671 BTK ENSG00000070756 PABPC1 H. sapiens SDL Slorth 0.9572 View
ENSG00000010671 BTK ENSG00000100138 SNU13 H. sapiens SDL Slorth 0.95695 View
ENSG00000010671 BTK ENSG00000146648 EGFR H. sapiens SDL Slorth 0.956923 View
ENSG00000010671 BTK ENSG00000128245 YWHAH H. sapiens SDL Slorth 0.956458 View
ENSG00000010671 BTK ENSG00000101412 E2F1 H. sapiens SDL Slorth 0.955364 View
ENSG00000010671 BTK ENSG00000026103 FAS H. sapiens SDL Slorth 0.955298 View