PDGFRB

ENSG00000113721 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004992 platelet activating factor receptor activity
GO:0005017 platelet-derived growth factor-activated receptor activity
GO:0005019 platelet-derived growth factor beta-receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0038085 vascular endothelial growth factor binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
MPN
AML
CMML
CML

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000105974 CAV1 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.964069 View
ENSG00000113721 PDGFRB ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.964017 View
ENSG00000072062 PRKACA ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.963969 View
ENSG00000113721 PDGFRB ENSG00000147403 RPL10 H. sapiens SDL Slorth 0.963853 View
ENSG00000103275 UBE2I ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.963592 View
ENSG00000113721 PDGFRB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.963519 View
ENSG00000113721 PDGFRB ENSG00000184634 MED12 H. sapiens SSL Slorth 0.963518 View
ENSG00000113721 PDGFRB ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.963491 View
ENSG00000082701 GSK3B ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.963451 View
ENSG00000113721 PDGFRB ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.963396 View
ENSG00000113721 PDGFRB ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.963396 View
ENSG00000113721 PDGFRB ENSG00000131467 PSME3 H. sapiens SDL Slorth 0.963377 View
ENSG00000113721 PDGFRB ENSG00000143420 ENSA H. sapiens SDL Slorth 0.963295 View
ENSG00000078140 UBE2K ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.963112 View
ENSG00000113721 PDGFRB ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.962978 View
ENSG00000113721 PDGFRB ENSG00000161547 SRSF2 H. sapiens SSL Slorth 0.962961 View
ENSG00000113721 PDGFRB ENSG00000136807 CDK9 H. sapiens SSL Slorth 0.962891 View
ENSG00000113721 PDGFRB ENSG00000140538 NTRK3 H. sapiens SDL Slorth 0.962887 View
ENSG00000113558 SKP1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.962766 View
ENSG00000113721 PDGFRB ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.962652 View
ENSG00000089159 PXN ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.962622 View
ENSG00000058404 CAMK2B ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.962561 View
ENSG00000113721 PDGFRB ENSG00000132849 PATJ H. sapiens SDL Slorth 0.962531 View
ENSG00000113721 PDGFRB ENSG00000136237 RAPGEF5 H. sapiens SDL Slorth 0.962506 View
ENSG00000061273 HDAC7 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.962472 View
ENSG00000113721 PDGFRB ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.962452 View
ENSG00000113721 PDGFRB ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.962431 View
ENSG00000113721 PDGFRB ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.962351 View
ENSG00000113721 PDGFRB ENSG00000164077 MON1A H. sapiens SDL Slorth 0.962312 View
ENSG00000101349 PAK5 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.962259 View
ENSG00000113721 PDGFRB ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.962245 View
ENSG00000113721 PDGFRB ENSG00000182511 FES H. sapiens SDL Slorth 0.962202 View
ENSG00000087274 ADD1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.962171 View
ENSG00000108830 RND2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.96214 View
ENSG00000113721 PDGFRB ENSG00000128052 KDR H. sapiens SSL Slorth 0.962032 View
ENSG00000113721 PDGFRB ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.962 View
ENSG00000113721 PDGFRB ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.961993 View
ENSG00000113721 PDGFRB ENSG00000151694 ADAM17 H. sapiens SDL Slorth 0.961975 View
ENSG00000113721 PDGFRB ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.961937 View
ENSG00000113721 PDGFRB ENSG00000116641 DOCK7 H. sapiens SDL Slorth 0.96192 View