MSH6

ENSG00000116062 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0030983 mismatched DNA binding
GO:0035064 methylated histone binding
GO:0042803 protein homodimerization activity
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0032137 guanine/thymine mispair binding
GO:0032142 single guanine insertion binding
GO:0032143 single thymine insertion binding
GO:0032357 oxidized purine DNA binding
GO:0032405 MutLalpha complex binding
GO:0043531 ADP binding
GO:0003677 DNA binding
GO:0000166 nucleotide binding
GO:0032138 single base insertion or deletion binding
GO:0003684 damaged DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
endometrial
ovarian

Orthologs

Gene Organism
MSH6 S. cerevisiae
msh-6 C. elegans
Msh6 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000116062 MSH6 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.818745 View
ENSG00000039068 CDH1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.818639 View
ENSG00000116062 MSH6 ENSG00000131759 RARA H. sapiens SSL Slorth 0.81739 View
ENSG00000116062 MSH6 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.817322 View
ENSG00000087586 AURKA ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.815981 View
ENSG00000077097 TOP2B ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.81521 View
ENSG00000116062 MSH6 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.815102 View
ENSG00000108953 YWHAE ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.81446 View
ENSG00000103126 AXIN1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.813372 View
ENSG00000116062 MSH6 ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.812859 View
ENSG00000072062 PRKACA ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.811312 View
ENSG00000116062 MSH6 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.811115 View
ENSG00000116062 MSH6 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.810064 View
ENSG00000115524 SF3B1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.809981 View
ENSG00000104738 MCM4 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.809646 View
ENSG00000116062 MSH6 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.809495 View
ENSG00000116062 MSH6 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.809488 View
ENSG00000116062 MSH6 ENSG00000170345 FOS H. sapiens SSL Slorth 0.807676 View
ENSG00000116062 MSH6 ENSG00000121774 KHDRBS1 H. sapiens SSL Slorth 0.805212 View
ENSG00000116062 MSH6 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.80403 View
ENSG00000116062 MSH6 ENSG00000124486 USP9X H. sapiens SSL Slorth 0.799956 View
ENSG00000116062 MSH6 ENSG00000150093 ITGB1 H. sapiens SSL Slorth 0.799205 View
ENSG00000104695 PPP2CB ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.796519 View
ENSG00000116062 MSH6 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.796334 View
ENSG00000116062 MSH6 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.796107 View
ENSG00000116062 MSH6 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.794974 View
ENSG00000116062 MSH6 ENSG00000124813 RUNX2 H. sapiens SSL Slorth 0.794954 View
ENSG00000101361 NOP56 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.793519 View
ENSG00000116062 MSH6 ENSG00000144028 SNRNP200 H. sapiens SSL Slorth 0.793432 View
ENSG00000094880 CDC23 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.792285 View
ENSG00000106211 HSPB1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.791805 View
ENSG00000102054 RBBP7 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.789378 View
ENSG00000004487 KDM1A ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.789219 View
ENSG00000116062 MSH6 ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.787934 View
ENSG00000116062 MSH6 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.787473 View
ENSG00000116062 MSH6 ENSG00000132341 RAN H. sapiens SSL Slorth 0.785368 View
ENSG00000116062 MSH6 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.785137 View
ENSG00000116062 MSH6 ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.782639 View
ENSG00000116062 MSH6 ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.782521 View
ENSG00000116062 MSH6 ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.782516 View