ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000108443 RPS6KB1 H. sapiens SSL BioGRID 1.0 View
ENSG00000097007 ABL1 ENSG00000140022 STON2 H. sapiens SDL Slorth 0.990618 View
ENSG00000097007 ABL1 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.989987 View
ENSG00000097007 ABL1 ENSG00000140299 BNIP2 H. sapiens SDL Slorth 0.989799 View
ENSG00000077254 USP33 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.988918 View
ENSG00000097007 ABL1 ENSG00000175592 FOSL1 H. sapiens SDL Slorth 0.988898 View
ENSG00000097007 ABL1 ENSG00000164056 SPRY1 H. sapiens SDL Slorth 0.988689 View
ENSG00000097007 ABL1 ENSG00000116688 MFN2 H. sapiens SDL Slorth 0.98845 View
ENSG00000097007 ABL1 ENSG00000120063 GNA13 H. sapiens SDL Slorth 0.988371 View
ENSG00000097007 ABL1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.988361 View
ENSG00000097007 ABL1 ENSG00000187098 MITF H. sapiens SDL Slorth 0.988122 View
ENSG00000097007 ABL1 ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.987868 View
ENSG00000097007 ABL1 ENSG00000112290 WASF1 H. sapiens SDL Slorth 0.987815 View
ENSG00000097007 ABL1 ENSG00000107223 EDF1 H. sapiens SDL Slorth 0.987695 View
ENSG00000097007 ABL1 ENSG00000100307 CBX7 H. sapiens SDL Slorth 0.987465 View
ENSG00000097007 ABL1 ENSG00000159593 NAE1 H. sapiens SDL Slorth 0.987431 View
ENSG00000097007 ABL1 ENSG00000117318 ID3 H. sapiens SDL Slorth 0.987383 View
ENSG00000097007 ABL1 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.987354 View
ENSG00000097007 ABL1 ENSG00000140332 TLE3 H. sapiens SDL Slorth 0.987274 View
ENSG00000097007 ABL1 ENSG00000119699 TGFB3 H. sapiens SDL Slorth 0.98721 View
ENSG00000097007 ABL1 ENSG00000123405 NFE2 H. sapiens SDL Slorth 0.987033 View
ENSG00000097007 ABL1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.987019 View
ENSG00000097007 ABL1 ENSG00000144283 PKP4 H. sapiens SDL Slorth 0.986956 View
ENSG00000097007 ABL1 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.98691 View
ENSG00000097007 ABL1 ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.986892 View
ENSG00000097007 ABL1 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.986886 View
ENSG00000097007 ABL1 ENSG00000129514 FOXA1 H. sapiens SDL Slorth 0.98688 View
ENSG00000097007 ABL1 ENSG00000121966 CXCR4 H. sapiens SDL Slorth 0.986852 View
ENSG00000097007 ABL1 ENSG00000116473 RAP1A H. sapiens SDL Slorth 0.986795 View
ENSG00000097007 ABL1 ENSG00000097033 SH3GLB1 H. sapiens SDL Slorth 0.986778 View
ENSG00000097007 ABL1 ENSG00000116731 PRDM2 H. sapiens SDL Slorth 0.98676 View
ENSG00000097007 ABL1 ENSG00000170242 USP47 H. sapiens SDL Slorth 0.986665 View
ENSG00000097007 ABL1 ENSG00000120948 TARDBP H. sapiens SDL Slorth 0.986572 View
ENSG00000097007 ABL1 ENSG00000198286 CARD11 H. sapiens SDL Slorth 0.986552 View
ENSG00000097007 ABL1 ENSG00000177105 RHOG H. sapiens SDL Slorth 0.986538 View
ENSG00000097007 ABL1 ENSG00000136158 SPRY2 H. sapiens SDL Slorth 0.986428 View
ENSG00000097007 ABL1 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.986415 View
ENSG00000097007 ABL1 ENSG00000269858 EGLN2 H. sapiens SDL Slorth 0.986286 View
ENSG00000097007 ABL1 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.986261 View
ENSG00000097007 ABL1 ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.986082 View