ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000162613 FUBP1 H. sapiens SDL Slorth 0.986069 View
ENSG00000097007 ABL1 ENSG00000151694 ADAM17 H. sapiens SDL Slorth 0.985998 View
ENSG00000097007 ABL1 ENSG00000140538 NTRK3 H. sapiens SDL Slorth 0.985898 View
ENSG00000097007 ABL1 ENSG00000101558 VAPA H. sapiens SDL Slorth 0.985888 View
ENSG00000097007 ABL1 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.985819 View
ENSG00000097007 ABL1 ENSG00000109756 RAPGEF2 H. sapiens SDL Slorth 0.985787 View
ENSG00000097007 ABL1 ENSG00000178188 SH2B1 H. sapiens SDL Slorth 0.985633 View
ENSG00000097007 ABL1 ENSG00000127314 RAP1B H. sapiens SDL Slorth 0.985417 View
ENSG00000097007 ABL1 ENSG00000148737 TCF7L2 H. sapiens SDL Slorth 0.985407 View
ENSG00000097007 ABL1 ENSG00000133104 SPG20 H. sapiens SDL Slorth 0.985389 View
ENSG00000097007 ABL1 ENSG00000174738 NR1D2 H. sapiens SDL Slorth 0.98538 View
ENSG00000097007 ABL1 ENSG00000144566 RAB5A H. sapiens SDL Slorth 0.985372 View
ENSG00000097007 ABL1 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.985329 View
ENSG00000097007 ABL1 ENSG00000169891 REPS2 H. sapiens SDL Slorth 0.985317 View
ENSG00000097007 ABL1 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.985288 View
ENSG00000097007 ABL1 ENSG00000197157 SND1 H. sapiens SDL Slorth 0.985252 View
ENSG00000097007 ABL1 ENSG00000155508 CNOT8 H. sapiens SDL Slorth 0.985249 View
ENSG00000097007 ABL1 ENSG00000134215 VAV3 H. sapiens SDL Slorth 0.985188 View
ENSG00000097007 ABL1 ENSG00000196923 PDLIM7 H. sapiens SDL Slorth 0.985103 View
ENSG00000097007 ABL1 ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.985075 View
ENSG00000097007 ABL1 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.985067 View
ENSG00000097007 ABL1 ENSG00000162961 DPY30 H. sapiens SDL Slorth 0.985026 View
ENSG00000097007 ABL1 ENSG00000105329 TGFB1 H. sapiens SDL Slorth 0.985025 View
ENSG00000097007 ABL1 ENSG00000141738 GRB7 H. sapiens SDL Slorth 0.984998 View
ENSG00000097007 ABL1 ENSG00000118217 ATF6 H. sapiens SDL Slorth 0.984845 View
ENSG00000097007 ABL1 ENSG00000115317 HTRA2 H. sapiens SDL Slorth 0.984831 View
ENSG00000097007 ABL1 ENSG00000213465 ARL2 H. sapiens SDL Slorth 0.984831 View
ENSG00000097007 ABL1 ENSG00000100505 TRIM9 H. sapiens SDL Slorth 0.984828 View
ENSG00000097007 ABL1 ENSG00000108924 HLF H. sapiens SDL Slorth 0.984735 View
ENSG00000097007 ABL1 ENSG00000135605 TEC H. sapiens SDL Slorth 0.984699 View
ENSG00000088367 EPB41L1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.984677 View
ENSG00000097007 ABL1 ENSG00000104517 UBR5 H. sapiens SDL Slorth 0.984625 View
ENSG00000097007 ABL1 ENSG00000155366 RHOC H. sapiens SDL Slorth 0.984618 View
ENSG00000097007 ABL1 ENSG00000168453 HR H. sapiens SDL Slorth 0.984571 View
ENSG00000097007 ABL1 ENSG00000131773 KHDRBS3 H. sapiens SDL Slorth 0.984562 View
ENSG00000097007 ABL1 ENSG00000105245 NUMBL H. sapiens SDL Slorth 0.98456 View
ENSG00000079335 CDC14A ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.984502 View
ENSG00000097007 ABL1 ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.984424 View
ENSG00000097007 ABL1 ENSG00000136754 ABI1 H. sapiens SDL Slorth 0.984404 View
ENSG00000097007 ABL1 ENSG00000107036 RIC1 H. sapiens SDL Slorth 0.984367 View