ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000118680 MYL12B H. sapiens SDL Slorth 0.983495 View
ENSG00000097007 ABL1 ENSG00000163625 WDFY3 H. sapiens SDL Slorth 0.983492 View
ENSG00000097007 ABL1 ENSG00000138674 SEC31A H. sapiens SDL Slorth 0.983464 View
ENSG00000097007 ABL1 ENSG00000182944 EWSR1 H. sapiens SDL Slorth 0.983444 View
ENSG00000085449 WDFY1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983417 View
ENSG00000097007 ABL1 ENSG00000221823 PPP3R1 H. sapiens SDL Slorth 0.983417 View
ENSG00000097007 ABL1 ENSG00000153071 DAB2 H. sapiens SDL Slorth 0.98336 View
ENSG00000097007 ABL1 ENSG00000172059 KLF11 H. sapiens SDL Slorth 0.983352 View
ENSG00000079432 CIC ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983335 View
ENSG00000097007 ABL1 ENSG00000107796 ACTA2 H. sapiens SDL Slorth 0.983293 View
ENSG00000097007 ABL1 ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.983262 View
ENSG00000097007 ABL1 ENSG00000138160 KIF11 H. sapiens SDL Slorth 0.983248 View
ENSG00000097007 ABL1 ENSG00000145555 MYO10 H. sapiens SDL Slorth 0.983234 View
ENSG00000097007 ABL1 ENSG00000188191 PRKAR1B H. sapiens SDL Slorth 0.983208 View
ENSG00000097007 ABL1 ENSG00000157456 CCNB2 H. sapiens SDL Slorth 0.983191 View
ENSG00000097007 ABL1 ENSG00000164171 ITGA2 H. sapiens SDL Slorth 0.983145 View
ENSG00000049323 LTBP1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983145 View
ENSG00000097007 ABL1 ENSG00000198258 UBL5 H. sapiens SDL Slorth 0.98312 View
ENSG00000097007 ABL1 ENSG00000198399 ITSN2 H. sapiens SDL Slorth 0.983102 View
ENSG00000097007 ABL1 ENSG00000143569 UBAP2L H. sapiens SDL Slorth 0.983102 View
ENSG00000097007 ABL1 ENSG00000111252 SH2B3 H. sapiens SDL Slorth 0.983079 View
ENSG00000097007 ABL1 ENSG00000164985 PSIP1 H. sapiens SDL Slorth 0.983072 View
ENSG00000097007 ABL1 ENSG00000162775 RBM15 H. sapiens SDL Slorth 0.983017 View
ENSG00000097007 ABL1 ENSG00000108387 SEPT4 H. sapiens SDL Slorth 0.98299 View
ENSG00000097007 ABL1 ENSG00000138443 ABI2 H. sapiens SDL Slorth 0.982986 View
ENSG00000097007 ABL1 ENSG00000124198 ARFGEF2 H. sapiens SDL Slorth 0.982948 View
ENSG00000097007 ABL1 ENSG00000140983 RHOT2 H. sapiens SDL Slorth 0.982903 View
ENSG00000097007 ABL1 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.982869 View
ENSG00000067829 IDH3G ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.98286 View
ENSG00000097007 ABL1 ENSG00000147140 NONO H. sapiens SDL Slorth 0.982854 View
ENSG00000097007 ABL1 ENSG00000152104 PTPN14 H. sapiens SDL Slorth 0.982832 View
ENSG00000008256 CYTH3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982813 View
ENSG00000097007 ABL1 ENSG00000135723 FHOD1 H. sapiens SDL Slorth 0.982792 View
ENSG00000076067 RBMS2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.98268 View
ENSG00000097007 ABL1 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.98266 View
ENSG00000097007 ABL1 ENSG00000147443 DOK2 H. sapiens SDL Slorth 0.982654 View
ENSG00000097007 ABL1 ENSG00000107929 LARP4B H. sapiens SDL Slorth 0.982651 View
ENSG00000097007 ABL1 ENSG00000178562 CD28 H. sapiens SDL Slorth 0.982566 View
ENSG00000097007 ABL1 ENSG00000126581 BECN1 H. sapiens SDL Slorth 0.98256 View
ENSG00000070718 AP3M2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982559 View