ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000086619 ERO1B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979088 View
ENSG00000079337 RAPGEF3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979088 View
ENSG00000097007 ABL1 ENSG00000105486 LIG1 H. sapiens SDL Slorth 0.979051 View
ENSG00000097007 ABL1 ENSG00000112144 ICK H. sapiens SDL Slorth 0.979045 View
ENSG00000089159 PXN ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979043 View
ENSG00000097007 ABL1 ENSG00000130766 SESN2 H. sapiens SDL Slorth 0.979032 View
ENSG00000097007 ABL1 ENSG00000113916 BCL6 H. sapiens SDL Slorth 0.979015 View
ENSG00000097007 ABL1 ENSG00000144935 TRPC1 H. sapiens SDL Slorth 0.979006 View
ENSG00000097007 ABL1 ENSG00000139220 PPFIA2 H. sapiens SDL Slorth 0.979004 View
ENSG00000097007 ABL1 ENSG00000151422 FER H. sapiens SDL Slorth 0.979002 View
ENSG00000097007 ABL1 ENSG00000138376 BARD1 H. sapiens SDL Slorth 0.979001 View
ENSG00000097007 ABL1 ENSG00000103496 STX4 H. sapiens SDL Slorth 0.979 View
ENSG00000085185 BCORL1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978995 View
ENSG00000097007 ABL1 ENSG00000152086 TUBA3E H. sapiens SDL Slorth 0.978982 View
ENSG00000097007 ABL1 ENSG00000118898 PPL H. sapiens SDL Slorth 0.978961 View
ENSG00000097007 ABL1 ENSG00000119866 BCL11A H. sapiens SDL Slorth 0.978958 View
ENSG00000023287 RB1CC1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978926 View
ENSG00000097007 ABL1 ENSG00000115232 ITGA4 H. sapiens SDL Slorth 0.978911 View
ENSG00000063438 AHRR ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978904 View
ENSG00000097007 ABL1 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.978859 View
ENSG00000097007 ABL1 ENSG00000185338 SOCS1 H. sapiens SDL Slorth 0.978849 View
ENSG00000097007 ABL1 ENSG00000187741 FANCA H. sapiens SDL Slorth 0.97884 View
ENSG00000097007 ABL1 ENSG00000196531 NACA H. sapiens SDL Slorth 0.978797 View
ENSG00000097007 ABL1 ENSG00000174791 RIN1 H. sapiens SDL Slorth 0.978793 View
ENSG00000097007 ABL1 ENSG00000134014 ELP3 H. sapiens SDL Slorth 0.978776 View
ENSG00000076201 PTPN23 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978774 View
ENSG00000097007 ABL1 ENSG00000242173 ARHGDIG H. sapiens SDL Slorth 0.978758 View
ENSG00000097007 ABL1 ENSG00000143882 ATP6V1C2 H. sapiens SDL Slorth 0.978757 View
ENSG00000097007 ABL1 ENSG00000168488 ATXN2L H. sapiens SDL Slorth 0.978732 View
ENSG00000097007 ABL1 ENSG00000137267 TUBB2A H. sapiens SDL Slorth 0.978727 View
ENSG00000097007 ABL1 ENSG00000154380 ENAH H. sapiens SDL Slorth 0.978695 View
ENSG00000011007 TCEB3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978674 View
ENSG00000097007 ABL1 ENSG00000113758 DBN1 H. sapiens SDL Slorth 0.97867 View
ENSG00000097007 ABL1 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.978664 View
ENSG00000097007 ABL1 ENSG00000166192 SENP8 H. sapiens SDL Slorth 0.978662 View
ENSG00000097007 ABL1 ENSG00000127481 UBR4 H. sapiens SDL Slorth 0.978623 View
ENSG00000090621 PABPC4 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978603 View
ENSG00000097007 ABL1 ENSG00000183853 KIRREL H. sapiens SDL Slorth 0.978601 View
ENSG00000097007 ABL1 ENSG00000128245 YWHAH H. sapiens SDL Slorth 0.978548 View
ENSG00000097007 ABL1 ENSG00000130429 ARPC1B H. sapiens SDL Slorth 0.978523 View