DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000119772 DNMT3A ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.905349 View
ENSG00000118513 MYB ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.904905 View
ENSG00000119772 DNMT3A ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.904791 View
ENSG00000119772 DNMT3A ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.90466 View
ENSG00000119772 DNMT3A ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.903902 View
ENSG00000119772 DNMT3A ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.903856 View
ENSG00000069869 NEDD4 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.903772 View
ENSG00000073111 MCM2 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.90249 View
ENSG00000119772 DNMT3A ENSG00000131747 TOP2A H. sapiens SSL Slorth 0.902403 View
ENSG00000119772 DNMT3A ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.901518 View
ENSG00000280548 FBL ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.901139 View
ENSG00000119772 DNMT3A ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.901078 View
ENSG00000119772 DNMT3A ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.900602 View
ENSG00000109320 NFKB1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.900191 View
ENSG00000100906 NFKBIA ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.89871 View
ENSG00000119772 DNMT3A ENSG00000198793 MTOR H. sapiens SSL Slorth 0.898489 View
ENSG00000119772 DNMT3A ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.897681 View
ENSG00000119772 DNMT3A ENSG00000254087 LYN H. sapiens SSL Slorth 0.896724 View
ENSG00000119772 DNMT3A ENSG00000185359 HGS H. sapiens SSL Slorth 0.895752 View
ENSG00000119772 DNMT3A ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.895617 View
ENSG00000119772 DNMT3A ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.894748 View
ENSG00000119772 DNMT3A ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.894712 View
ENSG00000119772 DNMT3A ENSG00000121774 KHDRBS1 H. sapiens SSL Slorth 0.89442 View
ENSG00000101966 XIAP ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.893912 View
ENSG00000094804 CDC6 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.893665 View
ENSG00000119772 DNMT3A ENSG00000131759 RARA H. sapiens SSL Slorth 0.892897 View
ENSG00000119772 DNMT3A ENSG00000144028 SNRNP200 H. sapiens SSL Slorth 0.890607 View
ENSG00000119772 DNMT3A ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.890585 View
ENSG00000055130 CUL1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.889867 View
ENSG00000110107 PRPF19 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.889435 View
ENSG00000119772 DNMT3A ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.888451 View
ENSG00000119772 DNMT3A ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.888152 View
ENSG00000119772 DNMT3A ENSG00000165731 RET H. sapiens SSL Slorth 0.888124 View
ENSG00000119772 DNMT3A ENSG00000121481 RNF2 H. sapiens SSL Slorth 0.887734 View
ENSG00000110713 NUP98 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.887526 View
ENSG00000080824 HSP90AA1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.887038 View
ENSG00000119772 DNMT3A ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.88671 View
ENSG00000117133 RPF1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.885997 View
ENSG00000102882 MAPK3 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.885236 View
ENSG00000116478 HDAC1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.885096 View