CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.974728 View
ENSG00000101266 CSNK2A1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.974591 View
ENSG00000131759 RARA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.974562 View
ENSG00000135446 CDK4 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.974535 View
ENSG00000135446 CDK4 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.974476 View
ENSG00000132155 RAF1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.974407 View
ENSG00000135446 CDK4 ENSG00000150907 FOXO1 H. sapiens SSL Slorth 0.974372 View
ENSG00000135446 CDK4 ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.974348 View
ENSG00000135446 CDK4 ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.974263 View
ENSG00000135446 CDK4 ENSG00000167085 PHB H. sapiens SSL Slorth 0.974245 View
ENSG00000135446 CDK4 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.973963 View
ENSG00000103194 USP10 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.973957 View
ENSG00000135446 CDK4 ENSG00000171223 JUNB H. sapiens SDL Slorth 0.973902 View
ENSG00000135446 CDK4 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.973882 View
ENSG00000135446 CDK4 ENSG00000144028 SNRNP200 H. sapiens SSL Slorth 0.973866 View
ENSG00000102882 MAPK3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.973861 View
ENSG00000135446 CDK4 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.973743 View
ENSG00000135446 CDK4 ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.973708 View
ENSG00000055130 CUL1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.973663 View
ENSG00000135446 CDK4 ENSG00000170315 UBB H. sapiens SDL Slorth 0.973508 View
ENSG00000135446 CDK4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.973257 View
ENSG00000121774 KHDRBS1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.973165 View
ENSG00000135446 CDK4 ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.973149 View
ENSG00000135446 CDK4 ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.972972 View
ENSG00000135446 CDK4 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.972814 View
ENSG00000135446 CDK4 ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.972769 View
ENSG00000135446 CDK4 ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.972683 View
ENSG00000135341 MAP3K7 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.97248 View
ENSG00000135446 CDK4 ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.972439 View
ENSG00000124762 CDKN1A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.972383 View
ENSG00000135446 CDK4 ENSG00000160145 KALRN H. sapiens SDL Slorth 0.972376 View
ENSG00000135446 CDK4 ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.972287 View
ENSG00000135446 CDK4 ENSG00000147133 TAF1 H. sapiens SSL Slorth 0.972248 View
ENSG00000135446 CDK4 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.97223 View
ENSG00000135446 CDK4 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.972224 View
ENSG00000135446 CDK4 ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.972214 View
ENSG00000135446 CDK4 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.972183 View
ENSG00000135446 CDK4 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972182 View
ENSG00000135446 CDK4 ENSG00000167552 TUBA1A H. sapiens SSL Slorth 0.972126 View
ENSG00000135446 CDK4 ENSG00000140464 PML H. sapiens SSL Slorth 0.972026 View