CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000084774 CAD ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.967258 View
ENSG00000135446 CDK4 ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.967239 View
ENSG00000135446 CDK4 ENSG00000141380 SS18 H. sapiens SDL Slorth 0.967165 View
ENSG00000135446 CDK4 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.967036 View
ENSG00000082898 XPO1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.966997 View
ENSG00000135446 CDK4 ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.966983 View
ENSG00000129152 MYOD1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.966983 View
ENSG00000135446 CDK4 ENSG00000136997 MYC H. sapiens SSL Slorth 0.966872 View
ENSG00000055130 CUL1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.966712 View
ENSG00000135446 CDK4 ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.966493 View
ENSG00000135446 CDK4 ENSG00000159461 AMFR H. sapiens SSL Slorth 0.966479 View
ENSG00000135446 CDK4 ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.966385 View
ENSG00000072401 UBE2D1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.966345 View
ENSG00000135446 CDK4 ENSG00000154767 XPC H. sapiens SDL Slorth 0.96628 View
ENSG00000058729 RIOK2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.966279 View
ENSG00000135446 CDK4 ENSG00000147162 OGT H. sapiens SSL Slorth 0.966256 View
ENSG00000094804 CDC6 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.966213 View
ENSG00000135446 CDK4 ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.966121 View
ENSG00000117748 RPA2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.966094 View
ENSG00000005007 UPF1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965984 View
ENSG00000073111 MCM2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.96593 View
ENSG00000135446 CDK4 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.965823 View
ENSG00000135446 CDK4 ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.965821 View
ENSG00000109332 UBE2D3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965817 View
ENSG00000135446 CDK4 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.965811 View
ENSG00000126261 UBA2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965804 View
ENSG00000123374 CDK2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.965753 View
ENSG00000135446 CDK4 ENSG00000204103 MAFB H. sapiens SDL Slorth 0.965715 View
ENSG00000134982 APC ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965638 View
ENSG00000109906 ZBTB16 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965599 View
ENSG00000135446 CDK4 ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.965463 View
ENSG00000135446 CDK4 ENSG00000184634 MED12 H. sapiens SSL Slorth 0.965402 View
ENSG00000103126 AXIN1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965398 View
ENSG00000070950 RAD18 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.965351 View
ENSG00000135446 CDK4 ENSG00000150907 FOXO1 H. sapiens SDL Slorth 0.965344 View
ENSG00000135446 CDK4 ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.96533 View
ENSG00000135446 CDK4 ENSG00000164109 MAD2L1 H. sapiens SSL Slorth 0.965143 View
ENSG00000135446 CDK4 ENSG00000163938 GNL3 H. sapiens SSL Slorth 0.964975 View
ENSG00000135446 CDK4 ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.964974 View
ENSG00000117676 RPS6KA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.96496 View