CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964884 View
ENSG00000121879 PIK3CA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964873 View
ENSG00000135446 CDK4 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.964793 View
ENSG00000135446 CDK4 ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.964758 View
ENSG00000063244 U2AF2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964595 View
ENSG00000121022 COPS5 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.964455 View
ENSG00000134853 PDGFRA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964378 View
ENSG00000111049 MYF5 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.964353 View
ENSG00000135446 CDK4 ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.964262 View
ENSG00000092201 SUPT16H ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964226 View
ENSG00000070010 UFD1L ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964211 View
ENSG00000135446 CDK4 ENSG00000165409 TSHR H. sapiens SDL Slorth 0.964204 View
ENSG00000135446 CDK4 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.964128 View
ENSG00000124181 PLCG1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964061 View
ENSG00000099956 SMARCB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963964 View
ENSG00000114423 CBLB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963876 View
ENSG00000062822 POLD1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963874 View
ENSG00000135446 CDK4 ENSG00000149136 SSRP1 H. sapiens SSL Slorth 0.963844 View
ENSG00000135446 CDK4 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.963821 View
ENSG00000110092 CCND1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.963595 View
ENSG00000078747 ITCH ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963579 View
ENSG00000105325 FZR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963558 View
ENSG00000135446 CDK4 ENSG00000136518 ACTL6A H. sapiens SSL Slorth 0.963524 View
ENSG00000047315 POLR2B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963365 View
ENSG00000116016 EPAS1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963353 View
ENSG00000104738 MCM4 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963249 View
ENSG00000021574 SPAST ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.963202 View
ENSG00000135446 CDK4 ENSG00000153147 SMARCA5 H. sapiens SSL Slorth 0.963102 View
ENSG00000135446 CDK4 ENSG00000178950 GAK H. sapiens SSL Slorth 0.963072 View
ENSG00000067829 IDH3G ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.963049 View
ENSG00000112118 MCM3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.963022 View
ENSG00000079156 OSBPL6 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.96292 View
ENSG00000135446 CDK4 ENSG00000147274 RBMX H. sapiens SSL Slorth 0.962577 View
ENSG00000113558 SKP1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.962418 View
ENSG00000072062 PRKACA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.962418 View
ENSG00000135446 CDK4 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.962202 View
ENSG00000135446 CDK4 ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.96218 View
ENSG00000135446 CDK4 ENSG00000154473 BUB3 H. sapiens SSL Slorth 0.962154 View
ENSG00000100906 NFKBIA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.962085 View
ENSG00000135446 CDK4 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.962075 View