DOT1L

ENSG00000104885 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0031151 histone methyltransferase activity (H3-K79 specific)
GO:0042054 histone methyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
DOT1 S. cerevisiae
gpp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000104885 DOT1L ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.812316 View
ENSG00000101161 PRPF6 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.80959 View
ENSG00000005007 UPF1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.809441 View
ENSG00000073111 MCM2 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.80939 View
ENSG00000104885 DOT1L ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.809254 View
ENSG00000104885 DOT1L ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.80597 View
ENSG00000104885 DOT1L ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.805945 View
ENSG00000104885 DOT1L ENSG00000117748 RPA2 H. sapiens SSL Slorth 0.804304 View
ENSG00000104885 DOT1L ENSG00000170345 FOS H. sapiens SSL Slorth 0.804052 View
ENSG00000094804 CDC6 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.80365 View
ENSG00000104885 DOT1L ENSG00000105974 CAV1 H. sapiens SSL Slorth 0.801674 View
ENSG00000104885 DOT1L ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.798599 View
ENSG00000104885 DOT1L ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.79475 View
ENSG00000104885 DOT1L ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.792033 View
ENSG00000104885 DOT1L ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.791514 View
ENSG00000104885 DOT1L ENSG00000126261 UBA2 H. sapiens SSL Slorth 0.790325 View
ENSG00000104885 DOT1L ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.789021 View
ENSG00000082898 XPO1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.788261 View
ENSG00000104885 DOT1L ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.785993 View
ENSG00000102882 MAPK3 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.785022 View
ENSG00000104885 DOT1L ENSG00000128908 INO80 H. sapiens SSL Slorth 0.783585 View
ENSG00000006451 RALA ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.783368 View
ENSG00000104885 DOT1L ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.78273 View
ENSG00000104885 DOT1L ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.782516 View
ENSG00000104885 DOT1L ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.778612 View
ENSG00000104885 DOT1L ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.778441 View
ENSG00000104885 DOT1L ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.777905 View
ENSG00000104885 DOT1L ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.777833 View
ENSG00000104885 DOT1L ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.775067 View
ENSG00000096968 JAK2 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.77481 View
ENSG00000104885 DOT1L ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.772606 View
ENSG00000104885 DOT1L ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.766284 View
ENSG00000099956 SMARCB1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.766279 View
ENSG00000078140 UBE2K ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.766134 View
ENSG00000104885 DOT1L ENSG00000141367 CLTC H. sapiens SSL Slorth 0.761795 View
ENSG00000058729 RIOK2 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.758981 View
ENSG00000104885 DOT1L ENSG00000114742 WDR48 H. sapiens SSL Slorth 0.75839 View
ENSG00000047315 POLR2B ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.7577 View
ENSG00000104885 DOT1L ENSG00000121774 KHDRBS1 H. sapiens SSL Slorth 0.755825 View
ENSG00000100906 NFKBIA ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.755452 View