SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000175387 SMAD2 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.958598 View
ENSG00000169800 RBMY1F ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.958572 View
ENSG00000113575 PPP2CA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.958568 View
ENSG00000175387 SMAD2 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.958542 View
ENSG00000103275 UBE2I ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.958528 View
ENSG00000175387 SMAD2 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.95851 View
ENSG00000023445 BIRC3 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.958465 View
ENSG00000141027 NCOR1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.958383 View
ENSG00000138069 RAB1A ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.95835 View
ENSG00000175387 SMAD2 ENSG00000239672 NME1 H. sapiens SDL Slorth 0.958344 View
ENSG00000175387 SMAD2 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.958244 View
ENSG00000164741 DLC1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.958112 View
ENSG00000120738 EGR1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.958045 View
ENSG00000077721 UBE2A ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.958032 View
ENSG00000118985 ELL2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.95802 View
ENSG00000175387 SMAD2 ENSG00000204842 ATXN2 H. sapiens SDL Slorth 0.957903 View
ENSG00000175387 SMAD2 ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.957888 View
ENSG00000175387 SMAD2 ENSG00000196712 NF1 H. sapiens SDL Slorth 0.957811 View
ENSG00000175387 SMAD2 ENSG00000198492 YTHDF2 H. sapiens SDL Slorth 0.957811 View
ENSG00000168148 HIST3H3 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957763 View
ENSG00000168487 BMP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.957758 View
ENSG00000175387 SMAD2 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.957737 View
ENSG00000101266 CSNK2A1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957724 View
ENSG00000153558 FBXL2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.957723 View
ENSG00000171791 BCL2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957629 View
ENSG00000175387 SMAD2 ENSG00000198909 MAP3K3 H. sapiens SSL Slorth 0.957567 View
ENSG00000149311 ATM ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957565 View
ENSG00000116030 SUMO1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957505 View
ENSG00000103194 USP10 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957478 View
ENSG00000175387 SMAD2 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.957425 View
ENSG00000169375 SIN3A ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957412 View
ENSG00000166167 BTRC ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957393 View
ENSG00000035928 RFC1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.957343 View
ENSG00000112062 MAPK14 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957254 View
ENSG00000012048 BRCA1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.95723 View
ENSG00000073584 SMARCE1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957223 View
ENSG00000139219 COL2A1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.95722 View
ENSG00000121022 COPS5 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957175 View
ENSG00000099804 CDC34 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.957157 View
ENSG00000010810 FYN ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.95712 View