SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000125740 FOSB ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972422 View
ENSG00000159692 CTBP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972409 View
ENSG00000015285 WAS ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972301 View
ENSG00000136997 MYC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972259 View
ENSG00000064012 CASP8 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972193 View
ENSG00000159216 RUNX1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972131 View
ENSG00000006468 ETV1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972109 View
ENSG00000117399 CDC20 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972107 View
ENSG00000123600 METTL8 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971976 View
ENSG00000149136 SSRP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971876 View
ENSG00000175387 SMAD2 ENSG00000196628 TCF4 H. sapiens SDL Slorth 0.971838 View
ENSG00000110330 BIRC2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971701 View
ENSG00000175387 SMAD2 ENSG00000197879 MYO1C H. sapiens SDL Slorth 0.971698 View
ENSG00000094804 CDC6 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971686 View
ENSG00000111049 MYF5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971651 View
ENSG00000128908 INO80 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971544 View
ENSG00000175387 SMAD2 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.971526 View
ENSG00000124782 RREB1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97152 View
ENSG00000175387 SMAD2 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.97148 View
ENSG00000165115 KIF27 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971365 View
ENSG00000148400 NOTCH1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971336 View
ENSG00000130766 SESN2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971326 View
ENSG00000131941 RHPN2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971205 View
ENSG00000117625 RCOR3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9712 View
ENSG00000165416 SUGT1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971088 View
ENSG00000105287 PRKD2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.971063 View
ENSG00000175387 SMAD2 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.971061 View
ENSG00000166851 PLK1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971049 View
ENSG00000123124 WWP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970973 View
ENSG00000008196 TFAP2B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970937 View
ENSG00000170836 PPM1D ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970931 View
ENSG00000138376 BARD1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970906 View
ENSG00000175387 SMAD2 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.970905 View
ENSG00000147010 SH3KBP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970885 View
ENSG00000100393 EP300 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970814 View
ENSG00000087995 METTL2A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970694 View
ENSG00000165055 METTL2B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970694 View
ENSG00000074219 TEAD2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970683 View
ENSG00000092421 SEMA6A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970681 View
ENSG00000117748 RPA2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970668 View