ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000158169 FANCC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.799416 View
ENSG00000138107 ACTR1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.799291 View
ENSG00000134352 IL6ST ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.799284 View
ENSG00000118971 CCND2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.798705 View
ENSG00000104885 DOT1L ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.798599 View
ENSG00000101557 USP14 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.798488 View
ENSG00000147573 TRIM55 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.798197 View
ENSG00000101442 ACTR5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.796693 View
ENSG00000175324 LSM1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.796553 View
ENSG00000129084 PSMA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.795388 View
ENSG00000085415 SEH1L ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.795092 View
ENSG00000119912 IDE ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.794363 View
ENSG00000034152 MAP2K3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.79413 View
ENSG00000108946 PRKAR1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.794039 View
ENSG00000178568 ERBB4 ENSG00000196923 PDLIM7 H. sapiens SSL Slorth 0.793813 View
ENSG00000076604 TRAF4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.793271 View
ENSG00000158828 PINK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.793218 View
ENSG00000175216 CKAP5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.792742 View
ENSG00000164754 RAD21 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.792638 View
ENSG00000178568 ERBB4 ENSG00000198836 OPA1 H. sapiens SSL Slorth 0.792347 View
ENSG00000105329 TGFB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.792286 View
ENSG00000011304 PTBP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.792132 View
ENSG00000166483 WEE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.792071 View
ENSG00000079785 DDX1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.79204 View
ENSG00000140941 MAP1LC3B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.791896 View
ENSG00000122566 HNRNPA2B1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.791677 View
ENSG00000152256 PDK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.791472 View
ENSG00000178568 ERBB4 ENSG00000185236 RAB11B H. sapiens SSL Slorth 0.791086 View
ENSG00000125630 POLR1B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.790679 View
ENSG00000132664 POLR3F ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.790579 View
ENSG00000157456 CCNB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.790125 View
ENSG00000118515 SGK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.790002 View
ENSG00000108510 MED13 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.789907 View
ENSG00000101849 TBL1X ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.789678 View
ENSG00000170004 CHD3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.788609 View
ENSG00000178568 ERBB4 ENSG00000220205 VAMP2 H. sapiens SSL Slorth 0.788547 View
ENSG00000178568 ERBB4 ENSG00000189403 HMGB1 H. sapiens SSL Slorth 0.788134 View
ENSG00000178568 ERBB4 ENSG00000197943 PLCG2 H. sapiens SSL Slorth 0.78722 View
ENSG00000134954 ETS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.787189 View
ENSG00000138443 ABI2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.787186 View