IGF1R

ENSG00000140443 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0031994 insulin-like growth factor I binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding

Drugs

Drug name Description
MECASERMIN Insulin-like growth factor I receptor agonist
MECASERMIN RINFABATE Insulin-like growth factor I receptor agonist

Diseases

No diseases in record

Orthologs

Gene Organism
daf-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000140443 IGF1R ENSG00000177239 MAN1B1 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000188130 MAPK12 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000198793 MTOR H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000114388 NPRL2 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000103148 NPRL3 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000171608 PIK3CD H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000102096 PIM2 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000253729 PRKDC H. sapiens SSL BioGRID 1.0 View
ENSG00000143761 ARF1 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000283094 PTEN H. sapiens SSL BioGRID 1.0 View
ENSG00000170340 B3GNT2 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000174903 RAB1B H. sapiens SSL BioGRID 1.0 View
ENSG00000168283 BMI1 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000111276 CDKN1B ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000147889 CDKN2A ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000154710 RABGEF1 H. sapiens SSL BioGRID 1.0 View
ENSG00000149554 CHEK1 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000149930 TAOK2 H. sapiens SSL BioGRID 1.0 View
ENSG00000100150 DEPDC5 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000274891 TRAPPC12 H. sapiens SSL BioGRID 1.0 View
ENSG00000094631 HDAC6 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000113597 TRAPPC13 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000136631 VPS45 H. sapiens SSL BioGRID 1.0 View
ENSG00000140443 IGF1R ENSG00000197081 IGF2R H. sapiens SSL BioGRID 1.0 View
ENSG00000080824 HSP90AA1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.985742 View
ENSG00000012048 BRCA1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.985484 View
ENSG00000091831 ESR1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.983768 View
ENSG00000100393 EP300 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.982071 View
ENSG00000005339 CREBBP ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.97861 View
ENSG00000116478 HDAC1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.978013 View
ENSG00000140443 IGF1R ENSG00000150991 UBC H. sapiens SDL Slorth 0.977813 View
ENSG00000133703 KRAS ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.97709 View
ENSG00000113575 PPP2CA ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.977031 View
ENSG00000135486 HNRNPA1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.974798 View
ENSG00000140443 IGF1R ENSG00000165409 TSHR H. sapiens SDL Slorth 0.974576 View
ENSG00000109670 FBXW7 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.972824 View
ENSG00000140443 IGF1R ENSG00000146648 EGFR H. sapiens SDL Slorth 0.972104 View
ENSG00000110395 CBL ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.971739 View
ENSG00000140443 IGF1R ENSG00000189067 LITAF H. sapiens SDL Slorth 0.971721 View
ENSG00000140443 IGF1R ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.969995 View