JAK3

ENSG00000105639 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding

Drugs

Drug name Description
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
acute megakaryocytic leukaemia
ETP ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000105639 JAK3 ENSG00000186716 BCR H. sapiens SSL Slorth 0.804086 View
ENSG00000058729 RIOK2 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.802819 View
ENSG00000080824 HSP90AA1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.799962 View
ENSG00000078140 UBE2K ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.79861 View
ENSG00000105639 JAK3 ENSG00000113712 CSNK1A1 H. sapiens SSL Slorth 0.798021 View
ENSG00000075624 ACTB ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.797369 View
ENSG00000105639 JAK3 ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.793973 View
ENSG00000104365 IKBKB ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.785514 View
ENSG00000073111 MCM2 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.782399 View
ENSG00000105639 JAK3 ENSG00000128245 YWHAH H. sapiens SSL Slorth 0.782229 View
ENSG00000105639 JAK3 ENSG00000109332 UBE2D3 H. sapiens SSL Slorth 0.780706 View
ENSG00000006451 RALA ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.780121 View
ENSG00000105639 JAK3 ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.77767 View
ENSG00000105639 JAK3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.776646 View
ENSG00000036257 CUL3 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.7742 View
ENSG00000069869 NEDD4 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.773336 View
ENSG00000105639 JAK3 ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.766988 View
ENSG00000094804 CDC6 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.766963 View
ENSG00000105639 JAK3 ENSG00000127022 CANX H. sapiens SSL Slorth 0.765146 View
ENSG00000105639 JAK3 ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.764535 View
ENSG00000064012 CASP8 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.762126 View
ENSG00000105639 JAK3 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.76192 View
ENSG00000105639 JAK3 ENSG00000182866 LCK H. sapiens SSL Slorth 0.75941 View
ENSG00000093009 CDC45 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.757251 View
ENSG00000084774 CAD ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.754911 View
ENSG00000105639 JAK3 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.752346 View
ENSG00000105639 JAK3 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.75058 View
ENSG00000105639 JAK3 ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.750504 View