KDR

ENSG00000128052 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0051879 Hsp90 protein binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
CABOZANTINIB
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
RAMUCIRUMAB Vascular endothelial growth factor receptor 2 inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
NSCLC
angiosarcoma
melanoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128052 KDR ENSG00000169252 ADRB2 H. sapiens SDL Slorth 0.935543 View
ENSG00000064012 CASP8 ENSG00000128052 KDR H. sapiens SSL Slorth 0.935182 View
ENSG00000128052 KDR ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.935089 View
ENSG00000128052 KDR ENSG00000134086 VHL H. sapiens SSL Slorth 0.935015 View
ENSG00000128052 KDR ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.935001 View
ENSG00000128052 KDR ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.934813 View
ENSG00000128052 KDR ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.934505 View
ENSG00000114062 UBE3A ENSG00000128052 KDR H. sapiens SSL Slorth 0.934491 View
ENSG00000100906 NFKBIA ENSG00000128052 KDR H. sapiens SSL Slorth 0.934485 View
ENSG00000053900 ANAPC4 ENSG00000128052 KDR H. sapiens SSL Slorth 0.93441 View
ENSG00000128052 KDR ENSG00000134853 PDGFRA H. sapiens SDL Slorth 0.93434 View
ENSG00000021574 SPAST ENSG00000128052 KDR H. sapiens SDL Slorth 0.934232 View
ENSG00000128052 KDR ENSG00000220205 VAMP2 H. sapiens SDL Slorth 0.934231 View
ENSG00000023445 BIRC3 ENSG00000128052 KDR H. sapiens SSL Slorth 0.933228 View
ENSG00000075785 RAB7A ENSG00000128052 KDR H. sapiens SSL Slorth 0.933177 View
ENSG00000128052 KDR ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.933042 View
ENSG00000128052 KDR ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.933002 View
ENSG00000128052 KDR ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.932642 View
ENSG00000128052 KDR ENSG00000136754 ABI1 H. sapiens SDL Slorth 0.932353 View
ENSG00000061938 TNK2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.932224 View
ENSG00000128052 KDR ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.932064 View
ENSG00000128052 KDR ENSG00000132170 PPARG H. sapiens SSL Slorth 0.931964 View
ENSG00000124164 VAPB ENSG00000128052 KDR H. sapiens SSL Slorth 0.931891 View
ENSG00000116016 EPAS1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.931787 View
ENSG00000128052 KDR ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.931689 View
ENSG00000128052 KDR ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.931521 View
ENSG00000071051 NCK2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.931456 View
ENSG00000067606 PRKCZ ENSG00000128052 KDR H. sapiens SSL Slorth 0.93134 View
ENSG00000128052 KDR ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.931263 View
ENSG00000128052 KDR ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.931193 View
ENSG00000117222 RBBP5 ENSG00000128052 KDR H. sapiens SSL Slorth 0.931118 View
ENSG00000026103 FAS ENSG00000128052 KDR H. sapiens SSL Slorth 0.930917 View
ENSG00000128052 KDR ENSG00000164867 NOS3 H. sapiens SDL Slorth 0.930614 View
ENSG00000128052 KDR ENSG00000283094 PTEN H. sapiens SDL Slorth 0.930524 View
ENSG00000113712 CSNK1A1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.929902 View
ENSG00000123124 WWP1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.929864 View
ENSG00000097007 ABL1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.929827 View
ENSG00000080986 NDC80 ENSG00000128052 KDR H. sapiens SSL Slorth 0.929705 View
ENSG00000112062 MAPK14 ENSG00000128052 KDR H. sapiens SDL Slorth 0.929598 View
ENSG00000128052 KDR ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.929379 View