KDR

ENSG00000128052 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0051879 Hsp90 protein binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
CABOZANTINIB
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
RAMUCIRUMAB Vascular endothelial growth factor receptor 2 inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
NSCLC
angiosarcoma
melanoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128052 KDR ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.920263 View
ENSG00000128052 KDR ENSG00000154447 SH3RF1 H. sapiens SDL Slorth 0.920206 View
ENSG00000075089 ACTR6 ENSG00000128052 KDR H. sapiens SSL Slorth 0.919946 View
ENSG00000128052 KDR ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.919525 View
ENSG00000116459 ATP5F1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.91938 View
ENSG00000128052 KDR ENSG00000164305 CASP3 H. sapiens SDL Slorth 0.918774 View
ENSG00000128052 KDR ENSG00000136997 MYC H. sapiens SDL Slorth 0.918644 View
ENSG00000128052 KDR ENSG00000157404 KIT H. sapiens SDL Slorth 0.918638 View
ENSG00000121481 RNF2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.91789 View
ENSG00000061938 TNK2 ENSG00000128052 KDR H. sapiens SDL Slorth 0.917811 View
ENSG00000080815 PSEN1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.917723 View
ENSG00000103479 RBL2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.917542 View
ENSG00000085511 MAP3K4 ENSG00000128052 KDR H. sapiens SSL Slorth 0.917441 View
ENSG00000063660 GPC1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.917346 View
ENSG00000128052 KDR ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.917334 View
ENSG00000105568 PPP2R1A ENSG00000128052 KDR H. sapiens SSL Slorth 0.917216 View
ENSG00000116473 RAP1A ENSG00000128052 KDR H. sapiens SSL Slorth 0.916504 View
ENSG00000106299 WASL ENSG00000128052 KDR H. sapiens SSL Slorth 0.916455 View
ENSG00000111540 RAB5B ENSG00000128052 KDR H. sapiens SDL Slorth 0.916442 View
ENSG00000128052 KDR ENSG00000178394 HTR1A H. sapiens SDL Slorth 0.915779 View
ENSG00000128052 KDR ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.91552 View
ENSG00000107643 MAPK8 ENSG00000128052 KDR H. sapiens SSL Slorth 0.915507 View
ENSG00000105737 GRIK5 ENSG00000128052 KDR H. sapiens SDL Slorth 0.914955 View
ENSG00000104695 PPP2CB ENSG00000128052 KDR H. sapiens SSL Slorth 0.914949 View
ENSG00000121774 KHDRBS1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.914944 View
ENSG00000079999 KEAP1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.914833 View
ENSG00000051382 PIK3CB ENSG00000128052 KDR H. sapiens SSL Slorth 0.914782 View
ENSG00000128052 KDR ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.914624 View
ENSG00000106245 BUD31 ENSG00000128052 KDR H. sapiens SSL Slorth 0.91444 View
ENSG00000087095 NLK ENSG00000128052 KDR H. sapiens SSL Slorth 0.914379 View
ENSG00000114554 PLXNA1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.91432 View
ENSG00000128052 KDR ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.913676 View
ENSG00000096968 JAK2 ENSG00000128052 KDR H. sapiens SDL Slorth 0.913633 View
ENSG00000128052 KDR ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.913623 View
ENSG00000102882 MAPK3 ENSG00000128052 KDR H. sapiens SDL Slorth 0.91355 View
ENSG00000102996 MMP15 ENSG00000128052 KDR H. sapiens SDL Slorth 0.913378 View
ENSG00000128052 KDR ENSG00000128881 TTBK2 H. sapiens SDL Slorth 0.913368 View
ENSG00000128052 KDR ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.913152 View
ENSG00000128052 KDR ENSG00000133216 EPHB2 H. sapiens SDL Slorth 0.913015 View
ENSG00000088986 DYNLL1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.912871 View