LCK

ENSG00000182866 - H. sapiens

Pathways

Go term Description
GO:0001948 glycoprotein binding
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016301 kinase activity
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0042169 SH2 domain binding
GO:0042609 CD4 receptor binding
GO:0042610 CD8 receptor binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0051117 ATPase binding

Drugs

Drug name Description
DASATINIB Tyrosine-protein kinase ABL inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
T-ALL

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000067141 NEO1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977475 View
ENSG00000135597 REPS1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977415 View
ENSG00000109670 FBXW7 ENSG00000182866 LCK H. sapiens SSL Slorth 0.977336 View
ENSG00000116478 HDAC1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977291 View
ENSG00000079432 CIC ENSG00000182866 LCK H. sapiens SDL Slorth 0.977219 View
ENSG00000066923 STAG3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977212 View
ENSG00000170624 SGCD ENSG00000182866 LCK H. sapiens SDL Slorth 0.977212 View
ENSG00000120500 ARR3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977186 View
ENSG00000070476 ZXDC ENSG00000182866 LCK H. sapiens SDL Slorth 0.977156 View
ENSG00000117400 MPL ENSG00000182866 LCK H. sapiens SDL Slorth 0.977144 View
ENSG00000171126 KCNG3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977122 View
ENSG00000142751 GPN2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977113 View
ENSG00000160193 WDR4 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977112 View
ENSG00000132669 RIN2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.977107 View
ENSG00000078114 NEBL ENSG00000182866 LCK H. sapiens SDL Slorth 0.977044 View
ENSG00000135776 ABCB10 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976953 View
ENSG00000168036 CTNNB1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976952 View
ENSG00000090889 KIF4A ENSG00000182866 LCK H. sapiens SDL Slorth 0.976945 View
ENSG00000145734 BDP1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97694 View
ENSG00000144488 ESPNL ENSG00000182866 LCK H. sapiens SDL Slorth 0.976924 View
ENSG00000141503 MINK1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976913 View
ENSG00000066455 GOLGA5 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97689 View
ENSG00000157216 SSBP3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97676 View
ENSG00000136944 LMX1B ENSG00000182866 LCK H. sapiens SDL Slorth 0.97676 View
ENSG00000182866 LCK ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.97669 View
ENSG00000102317 RBM3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976617 View
ENSG00000145506 NKD2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976595 View
ENSG00000128271 ADORA2A ENSG00000182866 LCK H. sapiens SDL Slorth 0.976587 View
ENSG00000145358 DDIT4L ENSG00000182866 LCK H. sapiens SDL Slorth 0.976575 View
ENSG00000116990 MYCL ENSG00000182866 LCK H. sapiens SDL Slorth 0.976499 View
ENSG00000165409 TSHR ENSG00000182866 LCK H. sapiens SDL Slorth 0.976475 View
ENSG00000166963 MAP1A ENSG00000182866 LCK H. sapiens SDL Slorth 0.976448 View
ENSG00000182866 LCK ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.976429 View
ENSG00000165832 TRUB1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97641 View
ENSG00000108830 RND2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976407 View
ENSG00000077380 DYNC1I2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976279 View
ENSG00000041982 TNC ENSG00000182866 LCK H. sapiens SDL Slorth 0.976204 View
ENSG00000072736 NFATC3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976168 View
ENSG00000166947 EPB42 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97614 View
ENSG00000006468 ETV1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.976 View