PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132437 DDC ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.973081 View
ENSG00000143799 PARP1 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.973073 View
ENSG00000108953 YWHAE ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.973023 View
ENSG00000143799 PARP1 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.973021 View
ENSG00000143799 PARP1 ENSG00000175093 SPSB4 H. sapiens SDL Slorth 0.973021 View
ENSG00000143799 PARP1 ENSG00000165806 CASP7 H. sapiens SDL Slorth 0.972912 View
ENSG00000136750 GAD2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972889 View
ENSG00000143799 PARP1 ENSG00000167258 CDK12 H. sapiens SDL Slorth 0.97278 View
ENSG00000143799 PARP1 ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.972752 View
ENSG00000107282 APBA1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972664 View
ENSG00000138376 BARD1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.972563 View
ENSG00000114554 PLXNA1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972466 View
ENSG00000143799 PARP1 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.972454 View
ENSG00000010671 BTK ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972401 View
ENSG00000143799 PARP1 ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.972262 View
ENSG00000127022 CANX ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.97226 View
ENSG00000143799 PARP1 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.972227 View
ENSG00000005339 CREBBP ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972209 View
ENSG00000117399 CDC20 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.972189 View
ENSG00000090889 KIF4A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972179 View
ENSG00000099365 STX1B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972097 View
ENSG00000143799 PARP1 ENSG00000168453 HR H. sapiens SDL Slorth 0.972086 View
ENSG00000143799 PARP1 ENSG00000166407 LMO1 H. sapiens SDL Slorth 0.972042 View
ENSG00000143799 PARP1 ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.971989 View
ENSG00000048462 TNFRSF17 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971948 View
ENSG00000123612 ACVR1C ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971948 View
ENSG00000143799 PARP1 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.971931 View
ENSG00000041982 TNC ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971901 View
ENSG00000005882 PDK2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971871 View
ENSG00000135723 FHOD1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971795 View
ENSG00000143799 PARP1 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.971777 View
ENSG00000143799 PARP1 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.971776 View
ENSG00000143033 MTF2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971762 View
ENSG00000143799 PARP1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.971752 View
ENSG00000143799 PARP1 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.971747 View
ENSG00000143799 PARP1 ENSG00000178999 AURKB H. sapiens SDL Slorth 0.971734 View
ENSG00000080815 PSEN1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.971684 View
ENSG00000143252 SDHC ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971593 View
ENSG00000117676 RPS6KA1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.971571 View
ENSG00000119048 UBE2B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.971485 View