SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YCR065W HCM1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.947401 View
YBR274W CHK1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.947074 View
YDL042C SIR2 YDL101C DUN1 S. cerevisiae SSL Slorth 0.946843 View
YDL042C SIR2 YOR244W ESA1 S. cerevisiae SSL Slorth 0.946646 View
YDL042C SIR2 YEL032W MCM3 S. cerevisiae SDL Slorth 0.946281 View
YDL042C SIR2 YJL074C SMC3 S. cerevisiae SSL Slorth 0.946175 View
YDL042C SIR2 YPL082C MOT1 S. cerevisiae SDL Slorth 0.946126 View
YDL042C SIR2 YLR045C STU2 S. cerevisiae SSL Slorth 0.94603 View
YBR060C ORC2 YDL042C SIR2 S. cerevisiae SSL Slorth 0.945648 View
YDL042C SIR2 YOR346W REV1 S. cerevisiae SDL Slorth 0.945575 View
YCR005C CIT2 YDL042C SIR2 S. cerevisiae SDL Slorth 0.945242 View
YDL042C SIR2 YOR033C EXO1 S. cerevisiae SSL Slorth 0.944139 View
YAL021C CCR4 YDL042C SIR2 S. cerevisiae SDL Slorth 0.943882 View
YDL042C SIR2 YNL113W RPC19 S. cerevisiae SDL Slorth 0.943797 View
YDL042C SIR2 YFL029C CAK1 S. cerevisiae SSL Slorth 0.943593 View
YDL042C SIR2 YER164W CHD1 S. cerevisiae SDL Slorth 0.943238 View
YAR002C-A ERP1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.94322 View
YDL042C SIR2 YGL163C RAD54 S. cerevisiae SSL Slorth 0.942523 View
YBL008W HIR1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.942513 View
YDL042C SIR2 YJL194W CDC6 S. cerevisiae SSL Slorth 0.942478 View
YDL042C SIR2 YNL088W TOP2 S. cerevisiae SDL Slorth 0.942239 View
YDL042C SIR2 YMR078C CTF18 S. cerevisiae SSL Slorth 0.942142 View
YDL042C SIR2 YNL330C RPD3 S. cerevisiae SSL Slorth 0.942048 View
YDL042C SIR2 YER020W GPA2 S. cerevisiae SDL Slorth 0.941922 View
YDL042C SIR2 YML069W POB3 S. cerevisiae SDL Slorth 0.94174 View
YDL042C SIR2 YPR141C KAR3 S. cerevisiae SSL Slorth 0.941731 View
YBR159W IFA38 YDL042C SIR2 S. cerevisiae SDL Slorth 0.941457 View
YDL042C SIR2 YER173W RAD24 S. cerevisiae SSL Slorth 0.940891 View
YDL042C SIR2 YNL312W RFA2 S. cerevisiae SSL Slorth 0.940867 View
YDL042C SIR2 YDR392W SPT3 S. cerevisiae SSL Slorth 0.940135 View
YBR243C ALG7 YDL042C SIR2 S. cerevisiae SDL Slorth 0.939968 View
YDL042C SIR2 YPL167C REV3 S. cerevisiae SSL Slorth 0.939844 View
YDL042C SIR2 YPL022W RAD1 S. cerevisiae SSL Slorth 0.939586 View
YBR103W SIF2 YDL042C SIR2 S. cerevisiae SSL Slorth 0.939198 View
YDL042C SIR2 YPL235W RVB2 S. cerevisiae SDL Slorth 0.938834 View
YBL008W HIR1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.938625 View
YBR154C RPB5 YDL042C SIR2 S. cerevisiae SDL Slorth 0.938322 View
YDL042C SIR2 YPR023C EAF3 S. cerevisiae SSL Slorth 0.937926 View
YDL042C SIR2 YML010W SPT5 S. cerevisiae SDL Slorth 0.937677 View
YDL042C SIR2 YDR145W TAF12 S. cerevisiae SSL Slorth 0.936184 View