SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YCR033W SNT1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.906634 View
YDL042C SIR2 YGL097W SRM1 S. cerevisiae SDL Slorth 0.906575 View
YBR177C EHT1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.905946 View
YDL042C SIR2 YOL012C HTZ1 S. cerevisiae SDL Slorth 0.905832 View
YCL045C EMC1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.905802 View
YDL042C SIR2 YDR099W BMH2 S. cerevisiae SDL Slorth 0.905644 View
YBR109C CMD1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.904999 View
YDL042C SIR2 YJL168C SET2 S. cerevisiae SSL Slorth 0.904822 View
YDL042C SIR2 YJL176C SWI3 S. cerevisiae SDL Slorth 0.904814 View
YAR003W SWD1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.904737 View
YCR066W RAD18 YDL042C SIR2 S. cerevisiae SSL Slorth 0.90438 View
YBR087W RFC5 YDL042C SIR2 S. cerevisiae SDL Slorth 0.904104 View
YDL042C SIR2 YDR146C SWI5 S. cerevisiae SDL Slorth 0.903698 View
YDL042C SIR2 YPR135W CTF4 S. cerevisiae SSL Slorth 0.903658 View
YDL042C SIR2 YOL006C TOP1 S. cerevisiae SDL Slorth 0.903505 View
YDL042C SIR2 YLR207W HRD3 S. cerevisiae SDL Slorth 0.903127 View
YDL042C SIR2 YER177W BMH1 S. cerevisiae SSL Slorth 0.902952 View
YDL042C SIR2 YOL004W SIN3 S. cerevisiae SSL Slorth 0.90275 View
YDL042C SIR2 YER171W RAD3 S. cerevisiae SDL Slorth 0.902737 View
YDL042C SIR2 YEL056W HAT2 S. cerevisiae SSL Slorth 0.90263 View
YDL042C SIR2 YPR119W CLB2 S. cerevisiae SDL Slorth 0.902183 View
YDL042C SIR2 YOR039W CKB2 S. cerevisiae SSL Slorth 0.902182 View
YDL042C SIR2 YMR190C SGS1 S. cerevisiae SSL Slorth 0.901756 View
YDL042C SIR2 YNL098C RAS2 S. cerevisiae SDL Slorth 0.901632 View
YDL042C SIR2 YJL030W MAD2 S. cerevisiae SDL Slorth 0.900915 View
YCL011C GBP2 YDL042C SIR2 S. cerevisiae SDL Slorth 0.900817 View
YBR112C CYC8 YDL042C SIR2 S. cerevisiae SSL Slorth 0.899267 View
YDL042C SIR2 YPL020C ULP1 S. cerevisiae SSL Slorth 0.895268 View
YDL042C SIR2 YLR418C CDC73 S. cerevisiae SSL Slorth 0.895022 View
YBR009C HHF1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.894341 View
YDL042C SIR2 YLR268W SEC22 S. cerevisiae SSL Slorth 0.891428 View
YDL042C SIR2 YJL030W MAD2 S. cerevisiae SSL Slorth 0.890271 View
YDL042C SIR2 YFL024C EPL1 S. cerevisiae SSL Slorth 0.890007 View
YBR202W MCM7 YDL042C SIR2 S. cerevisiae SSL Slorth 0.887502 View
YDL042C SIR2 YPR119W CLB2 S. cerevisiae SSL Slorth 0.886851 View
YDL042C SIR2 YNL113W RPC19 S. cerevisiae SSL Slorth 0.886278 View
YDL042C SIR2 YDL074C BRE1 S. cerevisiae SSL Slorth 0.885401 View
YDL042C SIR2 YHR164C DNA2 S. cerevisiae SSL Slorth 0.885086 View
YDL042C SIR2 YLR384C IKI3 S. cerevisiae SSL Slorth 0.884439 View
YBL023C MCM2 YDL042C SIR2 S. cerevisiae SSL Slorth 0.884083 View