SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000144749 LRIG1 H. sapiens SSL Slorth 0.776323 View
ENSG00000141646 SMAD4 ENSG00000165527 ARF6 H. sapiens SSL Slorth 0.776091 View
ENSG00000141646 SMAD4 ENSG00000145632 PLK2 H. sapiens SSL Slorth 0.775781 View
ENSG00000110955 ATP5B ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.775657 View
ENSG00000141646 SMAD4 ENSG00000158604 TMED4 H. sapiens SSL Slorth 0.775221 View
ENSG00000099995 SF3A1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.774986 View
ENSG00000141646 SMAD4 ENSG00000186591 UBE2H H. sapiens SSL Slorth 0.774315 View
ENSG00000141646 SMAD4 ENSG00000196911 KPNA5 H. sapiens SSL Slorth 0.773845 View
ENSG00000141646 SMAD4 ENSG00000160445 ZER1 H. sapiens SSL Slorth 0.773661 View
ENSG00000141646 SMAD4 ENSG00000164944 KIAA1429 H. sapiens SSL Slorth 0.773373 View
ENSG00000141646 SMAD4 ENSG00000204390 HSPA1L H. sapiens SSL Slorth 0.773231 View
ENSG00000141646 SMAD4 ENSG00000244038 DDOST H. sapiens SSL Slorth 0.773021 View
ENSG00000141646 SMAD4 ENSG00000163527 STT3B H. sapiens SSL Slorth 0.771217 View
ENSG00000141646 SMAD4 ENSG00000166869 CHP2 H. sapiens SSL Slorth 0.771205 View
ENSG00000105329 TGFB1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.770948 View
ENSG00000141646 SMAD4 ENSG00000152484 USP12 H. sapiens SSL Slorth 0.769805 View
ENSG00000080839 RBL1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.769406 View
ENSG00000141646 SMAD4 ENSG00000154710 RABGEF1 H. sapiens SSL Slorth 0.769322 View
ENSG00000141646 SMAD4 ENSG00000196498 NCOR2 H. sapiens SSL Slorth 0.769299 View
ENSG00000141646 SMAD4 ENSG00000156603 MED19 H. sapiens SSL Slorth 0.769046 View
ENSG00000112685 EXOC2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.768928 View
ENSG00000141646 SMAD4 ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.768455 View
ENSG00000111581 NUP107 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.768398 View
ENSG00000108055 SMC3 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.7681 View
ENSG00000141646 SMAD4 ENSG00000170525 PFKFB3 H. sapiens SSL Slorth 0.766449 View
ENSG00000096401 CDC5L ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.765969 View
ENSG00000141646 SMAD4 ENSG00000149292 TTC12 H. sapiens SSL Slorth 0.765939 View
ENSG00000141646 SMAD4 ENSG00000188130 MAPK12 H. sapiens SSL Slorth 0.765861 View
ENSG00000141646 SMAD4 ENSG00000157540 DYRK1A H. sapiens SSL Slorth 0.76576 View
ENSG00000141646 SMAD4 ENSG00000152520 PAN3 H. sapiens SSL Slorth 0.765659 View
ENSG00000141646 SMAD4 ENSG00000167996 FTH1 H. sapiens SSL Slorth 0.763428 View
ENSG00000141646 SMAD4 ENSG00000160075 SSU72 H. sapiens SSL Slorth 0.763089 View
ENSG00000053372 MRTO4 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.761775 View
ENSG00000141646 SMAD4 ENSG00000161542 PRPSAP1 H. sapiens SSL Slorth 0.761055 View
ENSG00000106636 YKT6 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.760774 View
ENSG00000141646 SMAD4 ENSG00000182578 CSF1R H. sapiens SSL Slorth 0.76036 View
ENSG00000134954 ETS1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.760306 View
ENSG00000141646 SMAD4 ENSG00000163110 PDLIM5 H. sapiens SSL Slorth 0.76021 View
ENSG00000141646 SMAD4 ENSG00000143437 ARNT H. sapiens SSL Slorth 0.759476 View
ENSG00000141646 SMAD4 ENSG00000154310 TNIK H. sapiens SSL Slorth 0.759092 View