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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
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Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
AFG3L2
ENSG00000141385
H. sapiens
ATP-dependent peptidase activity
metalloendopeptidase activity
protein binding
...
9
AGPAT1
ENSG00000235758
H. sapiens
1-acylglycerol-3-phosphate O-acyltransferase activity
1-acylglycerol-3-phosphate O-acyltransferase activity
1-acylglycerol-3-phosphate O-acyltransferase activity
...
2
AKT1
ENSG00000142208
H. sapiens
breast
colorectal
ovarian
NSCLC
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
...
3618
AKT2
ENSG00000105221
H. sapiens
ovarian
pancreatic
protein serine/threonine kinase activity
protein binding
ATP binding
...
206
ALAD
ENSG00000148218
H. sapiens
catalytic activity
porphobilinogen synthase activity
zinc ion binding
...
2
ALDH2
ENSG00000111275
H. sapiens
leiomyoma
DISULFIRAM
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
electron carrier activity
...
7
ALK
ENSG00000171094
H. sapiens
ALCL
NSCLC
neuroblastoma
inflammatory myofibroblastic tumour
Spitzoid tumour
CERITINIB
CRIZOTINIB
NF-kappaB-inducing kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
...
231
ALKBH3
ENSG00000166199
H. sapiens
protein binding
ferrous iron binding
L-ascorbic acid binding
...
1
ALKBH7
ENSG00000125652
H. sapiens
metal ion binding
dioxygenase activity
...
1
ALKBH8
ENSG00000137760
H. sapiens
tRNA binding
nucleotide binding
iron ion binding
...
21
ALPL
ENSG00000162551
H. sapiens
alkaline phosphatase activity
protein binding
pyrophosphatase activity
...
4
AMHR2
ENSG00000135409
H. sapiens
signal transducer, downstream of receptor, with serine/threonine kinase activity
receptor activity
transforming growth factor beta receptor activity, type II
...
7
ANAPC1
ENSG00000153107
H. sapiens
...
218
ANAPC13
ENSG00000129055
H. sapiens
protein binding
...
48
ANAPC4
ENSG00000053900
H. sapiens
ubiquitin-protein transferase activity
protein binding
protein phosphatase binding
...
405
ANKRD11
ENSG00000167522
H. sapiens
...
1
ANKZF1
ENSG00000163516
H. sapiens
protein binding
metal ion binding
thiol-dependent ubiquitin-specific protease activity
...
49
ANXA5
ENSG00000164111
H. sapiens
phospholipase inhibitor activity
calcium ion binding
protein binding
...
27
AOC1
ENSG00000002726
H. sapiens
receptor activity
copper ion binding
calcium ion binding
...
3
AOC3
ENSG00000131471
H. sapiens
copper ion binding
calcium ion binding
protein binding
...
13
AP2A1
ENSG00000196961
H. sapiens
protein binding
protein C-terminus binding
protein transporter activity
...
376
APC
ENSG00000134982
H. sapiens
colorectal
pancreatic
desmoid
hepatoblastoma
glioma
other CNS
protein binding
beta-catenin binding
microtubule binding
...
1401
APEX1
ENSG00000100823
H. sapiens
DNA binding
damaged DNA binding
double-stranded telomeric DNA binding
...
178
APOOL
ENSG00000155008
H. sapiens
protein binding
...
3
ARF1
ENSG00000143761
H. sapiens
magnesium ion binding
GTPase activity
signal transducer activity, downstream of receptor
...
326
ARFGAP2
ENSG00000149182
H. sapiens
GTPase activator activity
metal ion binding
...
158
ARGLU1
ENSG00000134884
H. sapiens
protein binding
cadherin binding involved in cell-cell adhesion
...
1
ARID1A
ENSG00000117713
H. sapiens
clear cell ovarian carcinoma
RCC
breast
DNA binding
transcription coactivator activity
protein binding
...
267
ARID1B
ENSG00000049618
H. sapiens
breast
hepatocellular carcinoma
DNA binding
transcription coactivator activity
protein binding
...
220
ARID2
ENSG00000189079
H. sapiens
hepatocellular carcinoma
DNA binding
protein binding
metal ion binding
...
277
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