NOTCH1 - PSMC3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
PSMC3	ENSG00000165916	No diseases in record	No drugs in record	transcription coactivator activity transcription corepressor activity protein binding ATP binding ATPase activity TBP-class protein binding proteasome-activating ATPase activity identical protein binding	RPT5 (S. cerevisiae) Rpt5 (D. melanogaster)