HDAC5 - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC5	ENSG00000108840	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN	RNA polymerase III transcription factor binding core promoter binding chromatin binding histone deacetylase activity protein kinase C binding protein binding transcription factor binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity histone deacetylase binding metal ion binding repressing transcription factor binding transcription regulatory region DNA binding	HDA1 (S. cerevisiae) hda-4 (C. elegans) HDAC4 (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)