DOT1L - NOTCH1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
DOT1L ENSG00000104885

No diseases in record

No drugs in record

DNA binding
protein binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K79 specific)
histone methyltransferase activity
DOT1 (S. cerevisiae)
gpp (D. melanogaster)
NOTCH1 ENSG00000148400 T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC

No drugs in record

core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
enzyme inhibitor activity
receptor activity
Notch binding
calcium ion binding
protein binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
protein heterodimerization activity
N (D. melanogaster)