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POLD1 - CASP8
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLD1
ENSG00000062822
CRC
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
POL3 (S. cerevisiae)
F10C2.4 (C. elegans)
DNApol-delta (D. melanogaster)
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)