ARNT - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARNT	ENSG00000143437	AML	No drugs in record	transcription factor activity, sequence-specific DNA binding transcription coactivator activity aryl hydrocarbon receptor activity protein binding transcription factor binding aryl hydrocarbon receptor binding enhancer binding protein heterodimerization activity transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding sequence-specific DNA binding	aha-1 (C. elegans) tgo (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)