ARNT - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARNT	ENSG00000143437	AML	No drugs in record	transcription factor activity, sequence-specific DNA binding transcription coactivator activity aryl hydrocarbon receptor activity protein binding transcription factor binding aryl hydrocarbon receptor binding enhancer binding protein heterodimerization activity transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding sequence-specific DNA binding	aha-1 (C. elegans) tgo (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)