RRM2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RRM2	ENSG00000171848	No diseases in record	GALLIUM NITRATE HYDROXYUREA	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding metal ion binding	RNR2 (S. cerevisiae) rnr-2 (C. elegans) RnrS (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)