RFC2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RFC2	ENSG00000049541	No diseases in record	No drugs in record	protein binding ATP binding enzyme binding DNA clamp loader activity single-stranded DNA-dependent ATPase activity DNA binding nucleotide binding purine nucleotide binding chromatin binding	RFC4 (S. cerevisiae) rfc-2 (C. elegans) RfC4 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)