MKNK1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MKNK1	ENSG00000079277	No diseases in record	No drugs in record	protein serine/threonine kinase activity calmodulin-dependent protein kinase activity protein binding calmodulin binding ATP binding calcium-dependent protein serine/threonine kinase activity	RCK1 (S. cerevisiae) RCK2 (S. cerevisiae) mnk-1 (C. elegans) Lk6 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)