RFC1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RFC1	ENSG00000035928	No diseases in record	No drugs in record	DNA binding DNA clamp loader activity double-stranded DNA binding protein binding ATP binding enzyme activator activity protein domain specific binding sequence-specific DNA binding nucleotide binding chromatin binding	RFC1 (S. cerevisiae) rfc-1 (C. elegans) Gnf1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)