SORT1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SORT1	ENSG00000134243	No diseases in record	No drugs in record	protein binding nerve growth factor receptor activity enzyme binding neurotensin receptor activity, non-G-protein coupled nerve growth factor binding	PEP1 (S. cerevisiae) VTH1 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)