VAPB - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VAPB	ENSG00000124164	No diseases in record	No drugs in record	protein binding microtubule binding enzyme binding FFAT motif binding protein homodimerization activity protein heterodimerization activity beta-tubulin binding cadherin binding involved in cell-cell adhesion	SCS2 (S. cerevisiae) SCS22 (S. cerevisiae) vpr-1 (C. elegans) F42G2.5 (C. elegans) fan (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)