MAP2K7 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K7	ENSG00000076984	No diseases in record	No drugs in record	magnesium ion binding signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding enzyme binding protein kinase binding protein phosphatase binding	PBS2 (S. cerevisiae) jkk-1 (C. elegans) sek-4 (C. elegans) hep (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)