NUP214 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NUP214	ENSG00000126883	AML T-ALL	No drugs in record	nuclear export signal receptor activity protein binding nuclear localization sequence binding structural constituent of nuclear pore nucleocytoplasmic transporter activity	npp-14 (C. elegans) Nup214 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)