POLD1 - DHFR

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
POLD1 ENSG00000062822 CRC
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
POL3 (S. cerevisiae)
F10C2.4 (C. elegans)
DNApol-delta (D. melanogaster)
DHFR ENSG00000228716

No diseases in record

METHOTREXATE
PEMETREXED
PRALATREXATE
mRNA binding
dihydrofolate reductase activity
folic acid binding
drug binding
folate reductase activity
methotrexate binding
NADPH binding
protein binding
NADP binding
DFR1 (S. cerevisiae)