SIRT1 - MEN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
MEN1	ENSG00000133895	parathyroid tumours pancreatic neuroendocrine tumour parathyroid adenoma pituitary adenoma pancreatic islet cell carcinoid	No drugs in record	four-way junction DNA binding Y-form DNA binding chromatin binding double-stranded DNA binding protein binding protein binding, bridging transcription regulatory region DNA binding protein N-terminus binding R-SMAD binding histone-lysine N-methyltransferase activity	Mnn1 (D. melanogaster)