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HDAC5 - WRN
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
HDAC5
ENSG00000108840
No diseases in record
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
RNA polymerase III transcription factor binding
core promoter binding
chromatin binding
histone deacetylase activity
protein kinase C binding
protein binding
transcription factor binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
histone deacetylase binding
metal ion binding
repressing transcription factor binding
transcription regulatory region DNA binding
HDA1 (S. cerevisiae)
hda-4 (C. elegans)
HDAC4 (D. melanogaster)
WRN
ENSG00000165392
osteosarcoma
meningioma
other tumour types
No drugs in record
magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)