PRKACA - SMAD5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKACA	ENSG00000072062	fibrolamellar hepatocellular carcinoma cortisol secreting adrenal adenoma	No drugs in record	protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding protein kinase A regulatory subunit binding	TPK1 (S. cerevisiae) TPK2 (S. cerevisiae) TPK3 (S. cerevisiae) kin-1 (C. elegans) Pka-C1 (D. melanogaster)
SMAD5	ENSG00000113658	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding metal ion binding	sma-3 (C. elegans) sma-2 (C. elegans)