TOP2A - MCM7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
MCM7	ENSG00000166508	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding DNA binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity chromatin binding DNA replication origin binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity single-stranded DNA-dependent ATPase activity hydrolase activity nucleotide binding ATP-dependent four-way junction helicase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM7 (S. cerevisiae) Mcm7 (D. melanogaster)